Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Trifluoroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 known ✓ | P27487 | 1/20 | 0.33 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL140346 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TSHRL3MBTL1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL27934780 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TSHRL3MBTL1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL8009450 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TSHRL3MBTL1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL4287600 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TSHRL3MBTL1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL4355857 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TSHRL3MBTL1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL1727596 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TSHRL3MBTL1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL3833376 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TSHRL3MBTL1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL5745817 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TSHRL3MBTL1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL18095558 | 0.97 | ALDH1A1 (0.33) | ALDH1A1TSHRL3MBTL1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL4296530 | 0.97 | ALDH1A1 (0.33) | ALDH1A1TSHRL3MBTL1DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1036 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118243799-A | Detection method of valsartan hydrochlorothiazide related substances | 珠海润都制药股份有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-117740970-A | Determination method of dissolution curve of sarcandesartan valsartan sodium tablet in dissolution medium with pH of 1.2 | 珠海润都制药股份有限公司 | 2024-03-22 | — | — | CN | claimed |
| CN-115656389-B | Method for measuring content of R-3-aminopiperidine dihydrochloride in alogliptin benzoate by using LC-MS | 重庆科瑞南海制药有限责任公司 | 2024-02-06 | — | — | CN | claimed |
| EP-3406591-B1 | DICAFFEOYL-SPERMIDINE DERIVATIVE GLYCOSIDE AND USE THEREOF | UNIV JINAN (CN) | 2023-09-06 | — | — | EP | claimed |
| CN-115792038-B | Method for detecting magnesium stearate in lamivudine tablet | 吉斯凯(苏州)制药有限公司 | 2023-08-22 | — | — | CN | claimed |
| CN-110732018-B | Preparation method of tuna meat ACE inhibitory peptide chewable tablets | 浙江海洋大学 | 2023-04-07 | — | — | CN | claimed |
| CN-115856125-A | Method for detecting 16 impurities in risperidone capsule | 宁波大红鹰药业股份有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-115792038-A | Method for detecting magnesium stearate in lamivudine tablets | 吉斯凯(苏州)制药有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-111233944-B | High performance liquid phase method for simultaneously preparing and separating four lignans components | 宝鸡市辰光生物科技有限公司 | 2023-02-28 | — | — | CN | claimed |
| CN-115656389-A | Method for determining content of R-3-aminopiperidine dihydrochloride in alogliptin benzoate by LC-MS (liquid chromatography-mass spectrometry) | 重庆科瑞南海制药有限责任公司 | 2023-01-31 | — | — | CN | claimed |
| CN-101718761-B | Method for measuring bovine tuberculin and activity thereof with high performance liquid chromatography | CHINA INST VETERINARY DRUGS CONTROL | 2012-08-29 | — | — | CN | claimed |
| CN-102645503-A | Detection method for vestigial protein in amoxicillin prepared by using enzymic method | UNITED LAB INNER MONGOLIA CO LTD | 2012-08-22 | — | — | CN | claimed |
| CN-101718761-A | Method for measuring bovine tuberculin and activity thereof with high performance liquid chromatography | CHINA INST OF VETERINARY DRUG | 2010-06-02 | — | — | CN | claimed |
| CN-101694487-A | Screening method, extracting method, content measuring method and application of glycyrrhisoflavone in liquorice | NINGXIA HUI AUTONOMOUS PREFECT | 2010-04-14 | — | — | CN | claimed |
| EP-1931693-A2 | PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES | CHEMAGIS LTD. (IL) | 2008-06-18 | — | — | EP | claimed |
| WO-2007092705-A2 | PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES | CHEMAGIS LTD. (IL) | 2007-08-16 | — | — | WO | claimed |
| US-20070191598-A1 | Process for Preparing Gemcitabine and Associated Intermediates | CHEMAGIS LTD. (IL) | 2007-08-16 | — | — | US | claimed |
| WO-2007027564-A2 | PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES | CHEMAGIS LTD. (IL) | 2007-03-08 | — | — | WO | claimed |
| US-20030130172-A1 | Novel lipoglycopeptide antibiotics | ELI LILLY AND COMPANY | 2003-07-10 | — | — | US | claimed |
| EP-0479899-B1 | VASODILATORY AND IMMUNE SUPPRESSANT PEPTIDES | HARVARD COLLEGE (US) | 1996-03-06 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130172-A1 | Novel lipoglycopeptide antibiotics | ENGASE, PGLS, LYPLA1 | DPP4 84/4885THRB 2669/4885ALDH1A1 4116/4885 |
| US-20070191598-A1 | Process for Preparing Gemcitabine and Associated Intermediates | DCTD, DPYD, THPO | DPP4 862/4885THRB 2449/4885ALDH1A1 718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.