Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10750706 | 0.75 | CYP3A4 (0.35) | CYP3A4TSHRMAPK1 | |
| SCHEMBL10976039 | 0.75 | CYP3A4 (0.35) | CYP3A4TSHRMAPK1 | |
| SCHEMBL3830970 | 0.74 | ESR1 (0.45) | CYP3A4MAPK1 | |
| SCHEMBL3834345 | 0.74 | ESR1 (0.45) | CYP3A4MAPK1 | |
| SCHEMBL39444 | 0.73 | TSHR (0.57) | CYP3A4TSHRMAPK1 | |
| SCHEMBL8109982 | 0.73 | TSHR (0.57) | CYP3A4TSHRMAPK1 | |
| SCHEMBL9327675 | 0.71 | CYP3A4 (0.38) | CYP3A4TSHRMAPK1 | |
| SCHEMBL11313294 | 0.71 | CYP3A4 (0.32) | CYP3A4TSHRMAPK1 | |
| SCHEMBL6401458 | 0.71 | CA1 (0.42) | CYP3A4TSHRMAPK1 | |
| SCHEMBL5988896 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363922-B1 | NOVEL HYDROXYARYL PHOSPHINE OXIDES MIXTURE, GLYCIDYL ETHERS AND EPOXY COMPOSITIONS, COMPOSITES AND LAMINATES DERIVED THEREFROM | GREAT LAKES CHEMICAL CORP (US) | 2006-07-26 | — | — | EP | claimed |
| US-10870724-B2 | High heat monomers and methods of use thereof | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-12-22 | — | — | US | disclosed |
| CN-106660953-B | High heat resistant monomers and methods of use thereof | 沙特基础工业全球技术有限公司 | 2020-07-28 | — | — | CN | disclosed |
| EP-3569591-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | SABIC Global Technologies B.V. (NL) | 2019-11-20 | — | — | EP | disclosed |
| US-20190337895-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2019-11-07 | — | — | US | disclosed |
| US-10465037-B2 | High heat monomers and methods of use thereof | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-11-05 | — | — | US | disclosed |
| US-10435368-B2 | High heat monomers and methods of use thereof | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-10-08 | — | — | US | disclosed |
| EP-3172188-B1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2019-09-04 | — | — | EP | disclosed |
| US-20170166528-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2017-06-15 | — | — | US | disclosed |
| US-20170158806-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2017-06-08 | — | — | US | disclosed |
| EP-1951814-A1 | POLY(ARYLENE ETHER) COMPOSITION, METHOD, AND ARTICLE | General Electric Company (US) | 2008-08-06 | — | — | EP | disclosed |
| EP-1940936-A1 | POLYMER COMPOSITION, METHOD, AND ARTICLE | General Electric Company (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007044312-A1 | POLY(ARYLENE ETHER) COMPOSITION, METHOD, AND ARTICLE | GENERAL ELECTRIC COMPANY (US) | 2007-04-19 | — | — | WO | disclosed |
| WO-2007044489-A1 | FLAME RETARDANT COMPOSITION AND METHOD | GENERAL ELECTRIC COMPANY (US) | 2007-04-19 | — | — | WO | disclosed |
| WO-2007044294-A1 | POLYMER COMPOSITION, METHOD, AND ARTICLE | GENERAL ELECTRIC COMPANY (US) | 2007-04-19 | — | — | WO | disclosed |
| US-20070080330-A1 | Flame retardant composition and method | CITIBANK, N.A., AS COLLATERAL AGENT | 2007-04-12 | — | — | US | disclosed |
| US-20070082986-A1 | Polymer composition, method, and article | SABIC GLOBAL TECHNOLOGIES IP B.V. (NL) | 2007-04-12 | — | — | US | disclosed |
| US-20070082987-A1 | Poly(arylene ether) composition, method, and article | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2007-04-12 | — | — | US | disclosed |
| US-5306835-A | Bis(phosphine)palladium complex; catalyst for the dimerization hydration reaction of 1,3-butadiene and water to octadienols | MITSUBISHI KASEI CORPORATION (JP) | 1994-04-26 | — | — | US | disclosed |
| US-5283377-A | Reacting butadiene/1,3-/ and water in the presence of a palladium compound, carbon dioxide and a triphenyl phsophine with electron donative substitutents | MITSUBISHI KASEI CORPORATION (JP) | 1994-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190337895-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | HSP90AA1, HSP90AB1, HSPBP1 | CYP3A4 2876/4885TSHR 4844/4885MAPK1 2752/4885 |
| US-10870724-B2 | High heat monomers and methods of use thereof | HSP90AA1, HSP90AB1, EPHX2 | CYP3A4 511/4885TSHR 4879/4885MAPK1 3243/4885 |
| US-20170158806-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | HSP90AA1, HSP90AB1, EPHX2 | CYP3A4 511/4885TSHR 4879/4885MAPK1 3243/4885 |
| US-10465037-B2 | High heat monomers and methods of use thereof | HSP90AA1, HSP90AB2P, HSP90AB1 | CYP3A4 432/4885TSHR 4878/4885MAPK1 3312/4885 |
| US-20170166528-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | HSP90AA1, HSP90AB1, HSPBP1 | CYP3A4 2876/4885TSHR 4844/4885MAPK1 2752/4885 |
| US-10435368-B2 | High heat monomers and methods of use thereof | HSP90AA1, HSP90AB1, HSPBP1 | CYP3A4 2876/4885TSHR 4844/4885MAPK1 2752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.