Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830970 | 0.96 | ESR1 (0.45) | ESR1ESR2SMN1; SMN2HTTACHE | |
| SCHEMBL12889878 | 0.78 | CYP3A4 (0.48) | ESR1ESR2ACHEGAALMNA | |
| SCHEMBL3833807 | 0.74 | CYP3A4 (0.38) | CYP3A4MAPK1 | |
| SCHEMBL6401458 | 0.72 | CA1 (0.42) | HTTACHEALDH1A1GAARAPGEF4 | |
| SCHEMBL3833957 | 0.71 | ESR1 (0.78) | ESR1ESR2ACHEALDH1A1LMNA | |
| SCHEMBL14586414 | 0.71 | SKP2 (0.45) | ESR1SMN1; SMN2HTTACHEALDH1A1 | |
| SCHEMBL5966312 | 0.70 | ACHE (0.68) | ESR1ESR2HTTACHEALDH1A1 | |
| SCHEMBL5966296 | 0.70 | ACHE (0.68) | ESR1ESR2HTTACHEALDH1A1 | |
| Bromide SCHEMBL10792390 | 0.69 | ESR1 (0.74) | ESR1ESR2ACHEALDH1A1LMNA | |
| Phenol SCHEMBL28870687 | 0.64 | CA12 (0.65) | ESR1ESR2SMN1; SMN2HTTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363922-B1 | NOVEL HYDROXYARYL PHOSPHINE OXIDES MIXTURE, GLYCIDYL ETHERS AND EPOXY COMPOSITIONS, COMPOSITES AND LAMINATES DERIVED THEREFROM | GREAT LAKES CHEMICAL CORP (US) | 2006-07-26 | — | — | EP | claimed |
| US-10870724-B2 | High heat monomers and methods of use thereof | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-12-22 | — | — | US | disclosed |
| EP-3569591-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | SABIC Global Technologies B.V. (NL) | 2019-11-20 | — | — | EP | disclosed |
| US-20190337895-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2019-11-07 | — | — | US | disclosed |
| US-10465037-B2 | High heat monomers and methods of use thereof | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-11-05 | — | — | US | disclosed |
| US-10435368-B2 | High heat monomers and methods of use thereof | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-10-08 | — | — | US | disclosed |
| EP-3172188-B1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2019-09-04 | — | — | EP | disclosed |
| US-20170166528-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2017-06-15 | — | — | US | disclosed |
| US-20170158806-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2017-06-08 | — | — | US | disclosed |
| EP-3172201-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | SABIC Global Technologies B.V. (NL) | 2017-05-31 | — | — | EP | disclosed |
| US-7495047-B2 | Poly(arylene ether) composition, method, and article | AT&T INTELLECTUAL PROPERTY, I, L.P. (US) | 2009-02-24 | — | — | US | disclosed |
| US-7488766-B2 | Polymer composition, method, and article | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-02-10 | — | — | US | disclosed |
| EP-1951814-A1 | POLY(ARYLENE ETHER) COMPOSITION, METHOD, AND ARTICLE | General Electric Company (US) | 2008-08-06 | — | — | EP | disclosed |
| EP-1940936-A1 | POLYMER COMPOSITION, METHOD, AND ARTICLE | General Electric Company (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007044312-A1 | POLY(ARYLENE ETHER) COMPOSITION, METHOD, AND ARTICLE | GENERAL ELECTRIC COMPANY (US) | 2007-04-19 | — | — | WO | disclosed |
| WO-2007044489-A1 | FLAME RETARDANT COMPOSITION AND METHOD | GENERAL ELECTRIC COMPANY (US) | 2007-04-19 | — | — | WO | disclosed |
| WO-2007044294-A1 | POLYMER COMPOSITION, METHOD, AND ARTICLE | GENERAL ELECTRIC COMPANY (US) | 2007-04-19 | — | — | WO | disclosed |
| US-20070082986-A1 | Polymer composition, method, and article | SABIC GLOBAL TECHNOLOGIES IP B.V. (NL) | 2007-04-12 | — | — | US | disclosed |
| US-20070080330-A1 | Flame retardant composition and method | CITIBANK, N.A., AS COLLATERAL AGENT | 2007-04-12 | — | — | US | disclosed |
| US-20070082987-A1 | Poly(arylene ether) composition, method, and article | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2007-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190337895-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | HSP90AA1, HSP90AB1, HSPBP1 | ESR1 2714/4885ESR2 2596/4885SMN1; SMN2 1855/4885 |
| US-10870724-B2 | High heat monomers and methods of use thereof | HSP90AA1, HSP90AB1, EPHX2 | ESR1 199/4885ESR2 138/4885SMN1; SMN2 2950/4885 |
| US-20170158806-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | HSP90AA1, HSP90AB1, EPHX2 | ESR1 199/4885ESR2 138/4885SMN1; SMN2 2950/4885 |
| US-10465037-B2 | High heat monomers and methods of use thereof | HSP90AA1, HSP90AB2P, HSP90AB1 | ESR1 193/4885ESR2 130/4885SMN1; SMN2 3190/4885 |
| US-20170166528-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | HSP90AA1, HSP90AB1, HSPBP1 | ESR1 2714/4885ESR2 2596/4885SMN1; SMN2 1855/4885 |
| US-10435368-B2 | High heat monomers and methods of use thereof | HSP90AA1, HSP90AB1, HSPBP1 | ESR1 2714/4885ESR2 2596/4885SMN1; SMN2 1855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.