Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | BAX | Q07812 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10798101 | 0.98 | LTA4H (0.55) | LTA4HTSHRNR1H2BAXMAOA | |
| SCHEMBL29177739 | 0.95 | LTA4H (0.50) | LTA4HTSHRNR1H2BAXMAOA | |
| SCHEMBL5966313 | 0.90 | LTA4H (0.69) | LTA4HTSHRPGR | |
| SCHEMBL3832572 | 0.90 | LTA4H (0.69) | LTA4HTSHRNR1H2BAXCA9 | |
| SCHEMBL3829920 | 0.90 | LTA4H (0.69) | LTA4HTSHRNR1H2BAXCA9 | |
| SCHEMBL20960602 | 0.88 | LTA4H (0.67) | LTA4HTSHRNR1H2BAXCA9 | |
| SCHEMBL15070046 | 0.86 | HTT (0.53) | LTA4HTSHRTDP1L3MBTL1LMNA | |
| SCHEMBL14148854 | 0.86 | LTA4H (0.63) | LTA4HPGRLMNA | |
| SCHEMBL8906687 | 0.86 | MAOA (0.63) | TSHRMAOAPARP10TDP1LMNA | |
| SCHEMBL14148731 | 0.86 | LTA4H (0.63) | LTA4HNR1H2BAXCA9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582691-B2 | Poly(arylene ether) compositions and articles | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-09-01 | — | — | US | claimed |
| JP-4311938-B2 | — | — | 2009-08-12 | — | — | JP | claimed |
| WO-2008089314-A1 | FLAME RETARDANT POLY (ARLENE ETHER) COMPOSITIONS AND ARTICLES | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-07-24 | — | — | WO | claimed |
| US-20080171817-A1 | POLY(ARYLENE ETHER) COMPOSITIONS AND ARTICLES | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2008-07-17 | — | — | US | claimed |
| US-7202311-B2 | Phosphine oxide hydroxyarl mixtures with novolac resins for co-curing epoxy resins | GREAT LAKES CORPORATION (US) | 2007-04-10 | — | — | US | claimed |
| EP-1363922-B1 | NOVEL HYDROXYARYL PHOSPHINE OXIDES MIXTURE, GLYCIDYL ETHERS AND EPOXY COMPOSITIONS, COMPOSITES AND LAMINATES DERIVED THEREFROM | GREAT LAKES CHEMICAL CORP (US) | 2006-07-26 | — | — | EP | claimed |
| US-20040225080-A1 | Phosphine oxide hydroxyaryl mixtures with novolac resins for co-curing epoxy resins | GREAT LAKES CHEMICAL CORPORATION | 2004-11-11 | — | — | US | claimed |
| JP-2004533413-A | — | — | 2004-11-04 | — | — | JP | claimed |
| US-20040121990-A1 | Novel hydroxyaryl phosphine oxides, glycidyl ethers and epoxy compositions, composites and laminates derived therefrom | GREAT LAKES CHEMICAL CORPORATION | 2004-06-24 | — | — | US | claimed |
| US-6733698-B2 | Mixture of mono-, bis- and tris-(hydroxyaryl) phosphine oxides useful to make polyglycidyl ethers or in epoxy compositions | PABU SERVICES, INC. | 2004-05-11 | — | — | US | claimed |
| EP-1363922-A2 | NOVEL HYDROXYARYL PHOSPHINE OXIDES, GLYCIDYL ETHERS AND EPOXY COMPOSITIONS, COMPOSITES AND LAMINATES DERIVED THEREFROM | Pabu Services, Inc. (US) | 2003-11-26 | — | — | EP | claimed |
| US-20030148109-A1 | Phosphine oxide hydroxyaryl mixtures with novolac resins for co-curing epoxy resins | CHEMTURA CORPORATION | 2003-08-07 | — | — | US | claimed |
| US-20020168527-A1 | Novel hydroxyaryl phosphine oxides, glycidyl ethers and epoxy compositions, composites and laminates derived therefrom | GREAT LAKES CHEMICAL CORPORATION | 2002-11-14 | — | — | US | claimed |
| WO-2002066485-A2 | NOVEL HYDROXYARYL PHOSPHINE OXIDES, GLYCIDYL ETHERS AND EPOXY COMPOSITIONS, COMPOSITES AND LAMINATES DERIVED THEREFROM | PABU SERVICES, INC. (US) | 2002-08-29 | — | — | WO | claimed |
| US-10870724-B2 | High heat monomers and methods of use thereof | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-12-22 | — | — | US | disclosed |
| CN-106660953-B | High heat resistant monomers and methods of use thereof | 沙特基础工业全球技术有限公司 | 2020-07-28 | — | — | CN | disclosed |
| EP-3569591-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | SABIC Global Technologies B.V. (NL) | 2019-11-20 | — | — | EP | disclosed |
| US-20050020801-A1 | Phosphine oxide hydroxyaryl mixtures with novolac resins for co-curing epoxy resins | GREAT LAKES CHEMICAL CORPORATION | 2005-01-27 | — | — | US | disclosed |
| US-20040225080-A1 | Phosphine oxide hydroxyaryl mixtures with novolac resins for co-curing epoxy resins | GREAT LAKES CHEMICAL CORPORATION | 2004-11-11 | — | — | US | disclosed |
| US-20030148109-A1 | Phosphine oxide hydroxyaryl mixtures with novolac resins for co-curing epoxy resins | CHEMTURA CORPORATION | 2003-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040121990-A1 | Novel hydroxyaryl phosphine oxides, glycidyl ethers and epoxy compositions, composites and laminates derived therefrom | PFAS, PTPMT1, PWWP2B | LTA4H 301/4885TSHR 4626/4885NR1H2 1357/4885 |
| US-10870724-B2 | High heat monomers and methods of use thereof | HSP90AA1, HSP90AB1, EPHX2 | LTA4H 155/4885TSHR 4879/4885NR1H2 609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.