Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.52 |
| ▸ | PAM | P19021 | 2/20 | 0.47 |
| ▸ | PRKCA | P17252 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3832870 | 0.97 | DGKA (0.48) | DGKAPAMPRKCATSHRMAPT | |
| SCHEMBL28002963 | 0.91 | DGKA (0.67) | DGKAPAMPRKCATSHRMAPT | |
| SCHEMBL3834143 | 0.91 | TSHR (0.50) | PAMTSHRLMNAALDH1A1HSD17B10 | |
| SCHEMBL10203127 | 0.91 | DGKA (0.67) | DGKAPAMPRKCATSHRMAPT | |
| SCHEMBL9064329 | 0.91 | DGKA (0.67) | DGKAPAMPRKCATSHRMAPT | |
| SCHEMBL19674961 | 0.90 | TSHR (0.46) | DGKAPAMPRKCATSHRMAPT | |
| SCHEMBL940267 | 0.89 | DGKA (0.42) | DGKAPAMPRKCATSHRMAPT | |
| SCHEMBL3832869 | 0.89 | TSHR (0.50) | PAMTSHRLMNAALDH1A1HSD17B10 | |
| SCHEMBL940422 | 0.89 | DGKA (0.42) | DGKAPAMPRKCATSHRMAPT | |
| SCHEMBL7760731 | 0.89 | DGKA (0.63) | DGKAPAMPRKCATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448508-B1 | DOUBLE ESTERS | DRUG DISCOVERY LAB AS (NO) | 2009-09-23 | — | — | EP | disclosed |
| EP-1448508-A1 | DOUBLE ESTERS | Photocure ASA (NO) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003045893-A1 | DOUBLE ESTERS | PHOTOCURE ASA (NO) | 2003-06-05 | — | — | WO | disclosed |