Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | PAM | P19021 | 2/20 | 0.38 |
| ▸ | PRKCA | P17252 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3832870 | 0.91 | DGKA (0.48) | DGKAPAMPRKCACYP1A2ALDH1A1 | |
| SCHEMBL3834147 | 0.89 | DGKA (0.52) | DGKAPAMPRKCACYP1A2ALDH1A1 | |
| SCHEMBL19674961 | 0.84 | TSHR (0.46) | DGKAPAMPRKCACYP1A2ALDH1A1 | |
| SCHEMBL3832869 | 0.83 | TSHR (0.50) | PAMALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL7760731 | 0.83 | DGKA (0.63) | DGKAPAMPRKCAALDH1A1LMNA | |
| SCHEMBL940422 | 0.83 | DGKA (0.42) | DGKAPAMPRKCACYP1A2ALDH1A1 | |
| SCHEMBL15635559 | 0.81 | ALDH1A1 (0.48) | DGKACYP1A2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL17084061 | 0.81 | ALDH1A1 (0.48) | DGKACYP1A2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL10203127 | 0.81 | DGKA (0.67) | DGKAPAMPRKCAALDH1A1LMNA | |
| SCHEMBL9064329 | 0.81 | DGKA (0.67) | DGKAPAMPRKCAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11560365-B2 | Non-fluorescent rhodamines | THE UNIVERSITY OF TOKYO (JP) | 2023-01-24 | — | — | US | disclosed |
| US-20210087160-A1 | NOVEL NON-FLUORESCENT RHODAMINES | THE UNIVERSITY OF TOKYO (JP) | 2021-03-25 | — | — | US | disclosed |
| US-20210072241-A1 | FLUORESCENT PROBE FOR DETECTING CARBOXYPEPTIDASE ACTIVITY | THE UNIVERSITY OF TOKYO (JP) | 2021-03-11 | — | — | US | disclosed |
| US-10815379-B2 | pH sensitive fluorescent probe | THE UNIVERSITY OF TOKYO (JP) | 2020-10-27 | — | — | US | disclosed |
| EP-3636653-A1 | ASYMMETRICAL SI RHODAMINE AND RHODOL SYNTHESIS | The University of Tokyo (JP) | 2020-04-15 | — | — | EP | disclosed |
| US-10004815-B2 | Near-infrared quenching group | THE UNIVERSITY OF TOKYO (JP) | 2018-06-26 | — | — | US | disclosed |
| US-20180118943-A1 | PH SENSITIVE FLUORESCENT PROBE | THE UNIVERSITY OF TOKYO (JP) | 2018-05-03 | — | — | US | disclosed |
| US-20180052105-A1 | SULFANE SULFUR-SELECTIVE FLUORESCENT PROBE | THE UNIVERSITY OF TOKYO (JP) | 2018-02-22 | — | — | US | disclosed |
| US-9714260-B2 | Asymmetrical Si rhodamine and rhodol synthesis | THE UNIVERSITY OF TOKYO (JP) | 2017-07-25 | — | — | US | disclosed |
| US-9688857-B2 | Fluorescent probe | THE UNIVERSITY OF TOKYO (JP) | 2017-06-27 | — | — | US | disclosed |
| US-20150353585-A1 | ASYMMETRICAL SI RHODAMINE AND RHODOL SYNTHESIS | THE UNIVERSITY OF TOKYO (JP) | 2015-12-10 | — | — | US | disclosed |
| US-9187499-B2 | Fluorescent probe | THE UNIVERSITY OF TOKYO (JP) | 2015-11-17 | — | — | US | disclosed |
| EP-2942352-A1 | ASYMMETRICAL Si RHODAMINE AND RHODOL SYNTHESIS | The University of Tokyo (JP) | 2015-11-11 | — | — | EP | disclosed |
| US-9170266-B2 | Fluorescent probe | THE UNIVERSITY OF TOKYO (JP) | 2015-10-27 | — | — | US | disclosed |
| US-20150212073-A1 | FLUORESCENT PROBE | THE UNIVERSITY OF TOKYO (JP) | 2015-07-30 | — | — | US | disclosed |
| US-20140057312-A1 | FLUORESCENT PROBE | THE UNIVERSITY OF TOKYO (JP) | 2014-02-27 | — | — | US | disclosed |
| US-20130289256-A1 | FLUORESCENT PROBE | THE UNIVERSITY OF TOKYO (JP) | 2013-10-31 | — | — | US | disclosed |
| US-7868147-B2 | substantially no fluorescent before the cleavage but highly fluorescent after the cleavage; traps a target substance such as an enzyme and emits fluorescence | Nagano, Tetsuo (JP) | 2011-01-11 | — | — | US | disclosed |
| US-20080014602-A1 | Fluorescent Probe | SEKISUI MEDICAL CO., LTD. (JP) | 2008-01-17 | — | — | US | disclosed |
| EP-1674579-A1 | FLUORESCENT PROBE | DAIICHI PURE CHEMICALS CO., LTD. (JP) | 2006-06-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087160-A1 | NOVEL NON-FLUORESCENT RHODAMINES | QTRT1, QTRT2, NONO | DGKA 2189/4885PAM 200/4885PRKCA 4494/4885 |
| US-20150353585-A1 | ASYMMETRICAL SI RHODAMINE AND RHODOL SYNTHESIS | RER1, SRR, SQLE | DGKA 2313/4885PAM 472/4885PRKCA 4214/4885 |
| US-20150212073-A1 | FLUORESCENT PROBE | SSTR3, SSTR1, SSTR5 | DGKA 3857/4885PAM 3823/4885PRKCA 4615/4885 |
| US-10815379-B2 | pH sensitive fluorescent probe | PHF6, PHF8, NHERF1 | DGKA 1497/4885PAM 946/4885PRKCA 1914/4885 |
| US-20210072241-A1 | FLUORESCENT PROBE FOR DETECTING CARBOXYPEPTIDASE ACTIVITY | CPN1, DNPEP, ANPEP | DGKA 4384/4885PAM 2118/4885PRKCA 3216/4885 |
| US-10004815-B2 | Near-infrared quenching group | CRY2, RELA, CRY1 | DGKA 2974/4885PAM 2716/4885PRKCA 4012/4885 |
| US-11560365-B2 | Non-fluorescent rhodamines | QTRT1, QTRT2, NONO | DGKA 2016/4885PAM 251/4885PRKCA 4503/4885 |
| US-20130289256-A1 | FLUORESCENT PROBE | HNRNPH3, H1-3, REL | DGKA 783/4885PAM 2649/4885PRKCA 4164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.