SCHEMBL7760731

SCHEMBL7760731

CCCCCC(=O)OCOC(C)=O

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.63
PAM P19021 2/20 0.57
TSHR P16473 1/20 0.53
MAPT P10636 1/20 0.53
PRKCA P17252 3/20 0.53
ALDH1A1 P00352 2/20 0.52
LMNA P02545 4/20 0.52
DNM1 Q05193 1/20 0.52
KDM4E B2RXH2 1/20 0.50
DUSP3 P51452 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
PRKCE Q02156 1/20 0.47
PRKCQ Q04759 1/20 0.47
PRKCD Q05655 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28002963 0.98 DGKA (0.67) DGKAPAMTSHRMAPTPRKCA
SCHEMBL9064329 0.98 DGKA (0.67) DGKAPAMTSHRMAPTPRKCA
SCHEMBL10203127 0.98 DGKA (0.67) DGKAPAMTSHRMAPTPRKCA
SCHEMBL28000638 0.93 ALDH1A1 (0.54) DGKAPAMTSHRMAPTPRKCA
SCHEMBL3832870 0.91 DGKA (0.48) DGKAPAMTSHRMAPTPRKCA
SCHEMBL3834162 0.91 DGKA (0.74) DGKAPAMTSHRMAPTPRKCA
SCHEMBL10911616 0.91 DGKA (0.74) DGKAPAMTSHRMAPTPRKCA
SCHEMBL3834147 0.89 DGKA (0.52) DGKAPAMTSHRMAPTPRKCA
SCHEMBL11226211 0.89 DGKA (0.78) DGKAPAMTSHRMAPTPRKCA
SCHEMBL11229514 0.89 DGKA (0.78) DGKAPAMTSHRMAPTPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001079379-A1 LIQUID-CRYSTAL MEDIUM HAVING A LOW THRESHOLD VOLTAGE MERCK PATENT GMBH (DE) 2001-10-25 WO disclosed
US-5252731-A Antibiotics FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-10-12 US disclosed
US-5110921-A Bactericides FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-05-05 US disclosed
US-4960889-A CEPHALOSPORIN INTERMEDIATES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-10-02 US disclosed
US-4731443-A 7-acylamino-3-vinylcephalosporanic acid derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-03-15 US disclosed
EP-0244637-A1 Starting compounds for 7-acylamino-3-vinylcephalosporanic acid derivatives and processes for their preparation FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1987-11-11 EP disclosed
EP-0030630-B1 7-ACYLAMINO-3-VINYLCEPHALOSPORANIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM; THEIR STARTING COMPOUNDS AND THEIR PREPARATION FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1987-04-01 EP disclosed
US-4585860-A ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-04-29 US disclosed
US-4487927-A BACTERICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-12-11 US disclosed
EP-0123024-A2 7-Acylamino-3-vinylcephalosporanic acid derivatives, processes for their preparation, pharmaceutical compositions containing them; their starting compounds and their preparation FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-10-31 EP disclosed
US-4423213-A ANTIBIOTIC FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-12-27 US disclosed
US-4409214-A Including cefixime; antibiotics FUJISAWA PHARMACEUTICAL, CO., LTD. (JP) 1983-10-11 US disclosed
EP-0030630-A2 7-Acylamino-3-vinylcephalosporanic acid derivatives, processes for their preparation, pharmaceutical compositions containing them; their starting compounds and their preparation FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-06-24 EP disclosed