SCHEMBL3834161

SCHEMBL3834161

Cl[Hf](Cl)([SiH2]Cc1ccccc1)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.35
HTR6 P50406 1/20 0.35
HTR2A P28223 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7715908 0.76 HTR6 (0.33) SIGMAR1HTR6HTR2A
SCHEMBL4469700 0.73 SIGMAR1 (0.35) SIGMAR1HTR6HTR2A
SCHEMBL3383074 0.70 HTR6 (0.33) SIGMAR1HTR6HTR2A
SCHEMBL215792 0.70 HTR2A (0.35) HTR6HTR2A
SCHEMBL7951352 0.70 HTR2A (0.35) SIGMAR1HTR6HTR2A
SCHEMBL3383168 0.70 HTR2A (0.35) SIGMAR1HTR6HTR2A
SCHEMBL4479589 0.69 HTR6 (0.33) SIGMAR1HTR6HTR2A
SCHEMBL15283338 0.69 HTR2A (0.36) SIGMAR1HTR6HTR2A
SCHEMBL6917975 0.68 HTR6 (0.32) SIGMAR1HTR6HTR2A
SCHEMBL4465783 0.68 HTR2A (0.35) SIGMAR1HTR6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1597632-B1 NON-MAGNETIC MONOCOMPONENT POSITIVE TONER COMPOSITION HAVING SUPERIOR TRANSFER EFFICIENCY LG CHEMICAL LTD (KR) 2013-03-27 EP claimed
EP-1597632-A4 NON-MAGNETIC MONOCOMPONENT POSITIVE TONER COMPOSITION HAVING SUPERIOR TRANSFER EFFICIENCY LG CHEMICAL LTD (KR) 2009-08-26 EP claimed
US-7378206-B2 Non-magnetic monocomponent positive toner composition having superior transfer efficiency LG CHEM, LTD. (KR) 2008-05-27 US claimed
US-20060105260-A1 Non-magnetic monocomponent positive toner composition having superior transfer efficiency LG CHEM, LTD. (KR) 2006-05-18 US claimed
EP-1597632-A1 NON-MAGNETIC MONOCOMPONENT POSITIVE TONER COMPOSITION HAVING SUPERIOR TRANSFER EFFICIENCY LG Chem, Ltd. (KR) 2005-11-23 EP claimed
WO-2004079456-A1 NON-MAGNETIC MONOCOMPONENT POSITIVE TONER COMPOSITION HAVING SUPERIOR TRANSFER EFFICIENCY LG CHEM, LTD. (KR) 2004-09-16 WO claimed
US-6641925-B1 Metallocene system catalyzed cycloolefin copolymer laminated to polyvinyl chloride; extrusion coated film as packaging TICONA GMBH (DE) 2003-11-04 US claimed
EP-0336127-B2 Process for preparing poly-alpha-olefins HOECHST AG (DE) 1997-04-09 EP claimed
EP-1597632-B1 NON-MAGNETIC MONOCOMPONENT POSITIVE TONER COMPOSITION HAVING SUPERIOR TRANSFER EFFICIENCY LG CHEMICAL LTD (KR) 2013-03-27 EP disclosed
EP-1597632-A4 NON-MAGNETIC MONOCOMPONENT POSITIVE TONER COMPOSITION HAVING SUPERIOR TRANSFER EFFICIENCY LG CHEMICAL LTD (KR) 2009-08-26 EP disclosed
US-7378206-B2 Non-magnetic monocomponent positive toner composition having superior transfer efficiency LG CHEM, LTD. (KR) 2008-05-27 US disclosed
US-20060105260-A1 Non-magnetic monocomponent positive toner composition having superior transfer efficiency LG CHEM, LTD. (KR) 2006-05-18 US disclosed
US-7026401-B1 Method of producing amorphous polyolefins with a wide mole weight distribution TICONA GMBH (DE) 2006-04-11 US disclosed
EP-1597632-A1 NON-MAGNETIC MONOCOMPONENT POSITIVE TONER COMPOSITION HAVING SUPERIOR TRANSFER EFFICIENCY LG Chem, Ltd. (KR) 2005-11-23 EP disclosed
US-5679811-A Hafnium metallocene compound HOECHST AKTIENGESELLSCHAFT (DE) 1997-10-21 US disclosed
US-5646220-A I.E. NORBORNENE-ETHYLENE COPOLYMERS; PHASE PROMOTERS HOECHST AKTIENGESELLSCHAFT (DE) 1997-07-08 US disclosed
US-5610253-A Cycloolefin polymers HOECHST AKTIENGESELLSCHAFT (DE) 1997-03-11 US disclosed
US-5422409-A Stopping polymerization when molecular weight distribution Mw/Mn is less than 2 HOECHST AKTIENGESELLSCHAFT 1995-06-06 US disclosed
US-5331057-A Cycloolefin block copolymers and a process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1994-07-19 US disclosed
US-5087677-A Catalyst of a metallocene and an aluminoxane HOECHST AKTIENGESELLSCHAFT (DE) 1992-02-11 US disclosed