Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2092213 | 1.00 | TSHR (0.34) | TSHRFAAHTRPV1EPHX2 | |
| SCHEMBL2091617 | 0.92 | TSHR (0.30) | TSHR | |
| SCHEMBL27352507 | 0.70 | EPHX2 (0.32) | TSHREPHX2 | |
| SCHEMBL948404 | 0.67 | ALDH1A1 (0.44) | — | |
| SCHEMBL3658335 | 0.67 | ALDH1A1 (0.44) | — | |
| SCHEMBL7503929 | 0.67 | ALDH1A1 (0.44) | — | |
| SCHEMBL6227336 | 0.67 | ALDH1A1 (0.44) | — | |
| SCHEMBL1148287 | 0.67 | ALDH1A1 (0.44) | — | |
| SCHEMBL20915220 | 0.67 | ALDH1A1 (0.44) | — | |
| SCHEMBL10952767 | 0.65 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1907010-A2 | PEPTIDES FOR USE IN THE TREATMENT OF OBESITY | Novo Nordisk A/S (DK) | 2008-04-09 | — | — | EP | claimed |
| WO-2007009894-A2 | PEPTIDES FOR USE IN THE TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2007-01-25 | — | — | WO | claimed |
| EP-2101822-A2 | USE OF PEPTIDES IN COMBINATION WITH SURGICAL INTERVENTION FOR THE TREATMENT OF OBESITY | Novo Nordisk A/S (DK) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008087190-A2 | USE OF PEPTIDES IN COMBINATION WITH SURGICAL INTERVENTION FOR THE TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2008-07-24 | — | — | WO | disclosed |
| EP-1907010-A2 | PEPTIDES FOR USE IN THE TREATMENT OF OBESITY | Novo Nordisk A/S (DK) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007009894-A2 | PEPTIDES FOR USE IN THE TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2007-01-25 | — | — | WO | disclosed |