SCHEMBL948404

SCHEMBL948404

CCCCCCCc1nnn[nH]1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
PKM P14618 1/20 0.44
HPGD P15428 1/20 0.44
GPR84 Q9NQS5 4/20 0.38
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7503929 1.00 ALDH1A1 (0.44) ALDH1A1PKMHPGDGPR84MAPT
SCHEMBL4521504 1.00 ALDH1A1 (0.44) ALDH1A1PKMHPGDGPR84MAPT
SCHEMBL10088355 1.00 ALDH1A1 (0.44) ALDH1A1PKMHPGDGPR84MAPT
SCHEMBL1148287 1.00 ALDH1A1 (0.44) ALDH1A1PKMHPGDGPR84MAPT
SCHEMBL11933712 1.00 ALDH1A1 (0.44) ALDH1A1PKMHPGDGPR84MAPT
SCHEMBL20915220 1.00 ALDH1A1 (0.44) ALDH1A1PKMHPGDGPR84MAPT
SCHEMBL2703075 1.00 ALDH1A1 (0.44) ALDH1A1PKMHPGDGPR84MAPT
SCHEMBL13519918 1.00 ALDH1A1 (0.44) ALDH1A1PKMHPGDGPR84MAPT
SCHEMBL16837384 1.00 ALDH1A1 (0.44) ALDH1A1PKMHPGDGPR84MAPT
SCHEMBL11933713 1.00 ALDH1A1 (0.44) ALDH1A1PKMHPGDGPR84MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3686207-B1 TETRAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF SHIKOKU CHEM (JP) 2024-10-23 EP disclosed
CN-114976010-B Negative electrode additive and preparation method and application thereof 深圳市研一新材料有限责任公司 2023-06-30 CN disclosed
CN-111108111-B Tetrazole silane compound, method for synthesizing the compound, and use thereof 四国化成工业株式会社 2023-05-02 CN disclosed
US-11472823-B2 Tetrazole silane compound, method for synthesizing said compound and use thereof SHIKOKU CHEMICALS CORPORATION (JP) 2022-10-18 US disclosed
US-20210179642-A1 TETRAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2021-06-17 US disclosed
CN-108079981-B Tetrazole/hydrophobic group bonded stationary phase and preparation method thereof 中国科学院大连化学物理研究所 2021-06-08 CN disclosed
US-11014946-B2 Tetrazole silane compound, method for synthesizing said compound and use thereof SHIKOKU CHEMICALS CORPORATION (JP) 2021-05-25 US disclosed
US-10975108-B2 2021-04-13 US disclosed
EP-3686207-A1 TETRAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF Shikoku Chemicals Corporation (JP) 2020-07-29 EP disclosed
US-20200223875-A1 TETRAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2020-07-16 US disclosed
US-20110009620-A1 4-Amino-5-cyanopyrimidine derivatives OTSUKA PHARMACEUTICAL CO., LTD. 2011-01-13 US disclosed
US-7834002-B2 4-amino-5-cyanopyrimidine derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2010-11-16 US disclosed
US-20100173835-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2010-07-08 US disclosed
US-20100173835-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2010-07-08 US disclosed
US-20080182854-A1 4-Amino-5-Cyanopyrimidine Derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2008-07-31 US disclosed
EP-1740574-B1 4-AMINO-5-CYANOPYRIMIDINE DERIVATIVES OTSUKA PHARMA CO LTD (JP) 2007-06-27 EP disclosed
EP-1740574-A2 4-AMINO-5-CYANOPYRIMIDINE DERIVATIVES Otsuka Pharmaceutical Company, Limited (JP) 2007-01-10 EP disclosed
WO-2005105778-A2 4-AMINO-5-CYANOPYRIMIDINE DERIVATIVES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-11-10 WO disclosed
US-4647572-A Iodoallyl and iodopropargyl substituted tetrazoles and anti-microbial compositions thereof MEIJI SEIKA KAISHA, LTD. (JP) 1987-03-03 US disclosed
EP-0107859-A1 Tetrazole compounds, process for preparing the same and antibacterial and antifungal compositions containing the same as active ingredient MEIJI SEIKA KAISHA LTD. (JP) 1984-05-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009620-A1 4-Amino-5-cyanopyrimidine derivatives ADORA2A, ADORA1, ADORA3 ALDH1A1 381/4885PKM 1983/4885HPGD 781/4885
US-20080182854-A1 4-Amino-5-Cyanopyrimidine Derivatives ADORA2A, ADORA1, ADORA3 ALDH1A1 381/4885PKM 1983/4885HPGD 781/4885
US-11472823-B2 Tetrazole silane compound, method for synthesizing said compound and use thereof TST, ITGA5, TPX2 ALDH1A1 1587/4885PKM 1852/4885HPGD 4209/4885
US-10975108-B2 ITGA5, ITGB5, ITGA1 ALDH1A1 845/4885PKM 3013/4885HPGD 3509/4885
US-20200223875-A1 TETRAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF TST, ITGA5, TPX2 ALDH1A1 1587/4885PKM 1852/4885HPGD 4209/4885
US-11014946-B2 Tetrazole silane compound, method for synthesizing said compound and use thereof TST, ITGA5, TPX2 ALDH1A1 1587/4885PKM 1852/4885HPGD 4209/4885
US-20100173835-A1 Peptides for Treatment of Obesity MC4R, GIPR, MC3R ALDH1A1 4086/4885PKM 2285/4885HPGD 3314/4885
US-20210179642-A1 TETRAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF TST, ITGA5, TPX2 ALDH1A1 1587/4885PKM 1852/4885HPGD 4209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.