SCHEMBL3658335

SCHEMBL3658335

CCCCCCc1nnn[nH]1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
PKM P14618 1/20 0.44
HPGD P15428 1/20 0.44
GPR84 Q9NQS5 4/20 0.38
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7503929 1.00 ALDH1A1 (0.44) ALDH1A1PKMHPGDGPR84MAPT
SCHEMBL4521504 1.00 ALDH1A1 (0.44) ALDH1A1PKMHPGDGPR84MAPT
SCHEMBL10088355 1.00 ALDH1A1 (0.44) ALDH1A1PKMHPGDGPR84MAPT
SCHEMBL1148287 1.00 ALDH1A1 (0.44) ALDH1A1PKMHPGDGPR84MAPT
SCHEMBL11933712 1.00 ALDH1A1 (0.44) ALDH1A1PKMHPGDGPR84MAPT
SCHEMBL20915220 1.00 ALDH1A1 (0.44) ALDH1A1PKMHPGDGPR84MAPT
SCHEMBL2703075 1.00 ALDH1A1 (0.44) ALDH1A1PKMHPGDGPR84MAPT
SCHEMBL13519918 1.00 ALDH1A1 (0.44) ALDH1A1PKMHPGDGPR84MAPT
SCHEMBL16837384 1.00 ALDH1A1 (0.44) ALDH1A1PKMHPGDGPR84MAPT
SCHEMBL11933713 1.00 ALDH1A1 (0.44) ALDH1A1PKMHPGDGPR84MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107325078-A A kind of preparation method of Cilostazol 烟台万润药业有限公司 2017-11-07 CN claimed
EP-4722199-A1 AZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID AZOLE COMPOUND, AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2026-04-08 EP disclosed
WO-2024247919-A1 AZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID AZOLE COMPOUND, AND USE THEREOF 四国化成工業株式会社 2024-12-05 WO disclosed
EP-3686207-B1 TETRAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF SHIKOKU CHEM (JP) 2024-10-23 EP disclosed
CN-111108111-B Tetrazole silane compound, method for synthesizing the compound, and use thereof 四国化成工业株式会社 2023-05-02 CN disclosed
US-11472823-B2 Tetrazole silane compound, method for synthesizing said compound and use thereof SHIKOKU CHEMICALS CORPORATION (JP) 2022-10-18 US disclosed
US-20210179642-A1 TETRAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2021-06-17 US disclosed
US-11014946-B2 Tetrazole silane compound, method for synthesizing said compound and use thereof SHIKOKU CHEMICALS CORPORATION (JP) 2021-05-25 US disclosed
US-10975108-B2 2021-04-13 US disclosed
EP-3686207-A1 TETRAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF Shikoku Chemicals Corporation (JP) 2020-07-29 EP disclosed
US-20100222269-A1 IMPROVED DERIVATIVES OF AMYLIN NOVO NORDISK A/S (DK) 2010-09-02 US disclosed
EP-2207773-A2 HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF Otsuka Pharmaceutical Co., Ltd. (JP) 2010-07-21 EP disclosed
WO-2009057811-A2 HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2009-05-07 WO disclosed
US-20080280836-A1 Anti-hypercholesterolemic biaryl azetidinone compounds MORRIELLO GREGORI J 2008-11-13 US disclosed
US-20080242091-A1 METAL-POLISHING LIQUID AND POLISHING METHOD FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080143649-A1 DISPLAY DEVICE AND DISPLAY UNIT SONY CORPORATION (JP) 2008-06-19 US disclosed
EP-1859782-A1 Composition for coloring and/or lightening human hair comprising tetrazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed
EP-0230783-B1 DIESEL FUEL CONTAINING A TETRAZOLE OR TRIAZOLE CETANE IMPROVER EXXON CHEMICAL PATENTS INC. (US) 1990-01-03 EP disclosed
US-4632674-A Diesel fuel containing a tetrazole or triazole cetane improver EXXON CHEMICAL PATENTS INC. (US) 1986-12-30 US disclosed
EP-0145434-A2 Novel dihydropyridine derivatives and process for preparing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1985-06-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080280836-A1 Anti-hypercholesterolemic biaryl azetidinone compounds APOB, PCSK9, CYP46A1 ALDH1A1 1045/4885PKM 2414/4885HPGD 2837/4885
US-20100222269-A1 IMPROVED DERIVATIVES OF AMYLIN IAPP, GLP1R, ALB ALDH1A1 4616/4885PKM 4268/4885HPGD 4447/4885
US-11472823-B2 Tetrazole silane compound, method for synthesizing said compound and use thereof TST, ITGA5, TPX2 ALDH1A1 1587/4885PKM 1852/4885HPGD 4209/4885
US-10975108-B2 ITGA5, ITGB5, ITGA1 ALDH1A1 845/4885PKM 3013/4885HPGD 3509/4885
US-11014946-B2 Tetrazole silane compound, method for synthesizing said compound and use thereof TST, ITGA5, TPX2 ALDH1A1 1587/4885PKM 1852/4885HPGD 4209/4885
US-20210179642-A1 TETRAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF TST, ITGA5, TPX2 ALDH1A1 1587/4885PKM 1852/4885HPGD 4209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.