Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.58 |
| ▸ | ITGAV | P06756 | 10/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 4/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382456 | 0.89 | ITGB3 (0.47) | ITGB3ITGAVITGA2BLMNAPKM | |
| SCHEMBL7662919 | 0.86 | ITGB3 (0.65) | ITGB3ITGAVITGA2BLMNAPKM | |
| SCHEMBL383437 | 0.85 | ITGB3 (0.47) | ITGB3ITGAVITGA2BLMNAPKM | |
| SCHEMBL383582 | 0.85 | ITGB3 (0.59) | ITGB3ITGAVITGA2BALDH1A1 | |
| SCHEMBL6497814 | 0.84 | ITGB3 (0.41) | ITGB3ITGAVITGA2BVDR | |
| SCHEMBL383095 | 0.81 | ITGB3 (0.46) | ITGB3ITGAVITGA2B | |
| SCHEMBL382188 | 0.80 | ITGB3 (0.49) | ITGB3ITGAVITGA2B | |
| SCHEMBL382656 | 0.79 | ITGB3 (0.63) | ITGB3ITGAVITGA2BLMNAPKM | |
| SCHEMBL383158 | 0.78 | ITGB3 (0.44) | ITGB3ITGAVITGA2BLMNAALDH1A1 | |
| SCHEMBL27360304 | 0.77 | ITGB3 (0.66) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |