Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.51 |
| ▸ | ITGAV | P06756 | 14/20 | 0.51 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664581 | 0.90 | ITGB3 (0.64) | ITGB3ITGA2BITGAV | |
| SCHEMBL383160 | 0.84 | ITGAV (0.58) | ITGB3ITGA2BITGAVITGA2 | |
| SCHEMBL382572 | 0.80 | ITGAV (0.53) | ITGB3ITGA2BITGAVITGA2 | |
| SCHEMBL383584 | 0.80 | ITGB3 (0.77) | ITGB3ITGA2BITGAV | |
| SCHEMBL460324 | 0.78 | ITGAV (0.53) | ITGB3ITGA2BITGAVITGA2 | |
| SCHEMBL382659 | 0.77 | ITGAV (0.51) | ITGB3ITGA2BITGAV | |
| SCHEMBL6499264 | 0.76 | ITGAV (0.49) | ITGB3ITGA2BITGAVITGA2 | |
| SCHEMBL7470163 | 0.76 | ITGB3 (0.54) | ITGB3ITGA2BITGAV | |
| SCHEMBL383097 | 0.75 | ITGAV (0.60) | ITGB3ITGA2BITGAV | |
| SCHEMBL7658148 | 0.75 | ITGB3 (0.68) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |