Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.46 |
| ▸ | TPSD1 | Q9BZJ3 | 4/20 | 0.46 |
| ▸ | TPSG1 | Q9NRR2 | 4/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38334 | 1.00 | TPSAB1 (0.46) | TPSAB1TPSD1TPSG1ERCC1ERCC4 | |
| SCHEMBL14678611 | 1.00 | TPSAB1 (0.46) | TPSAB1TPSD1TPSG1ERCC1ERCC4 | |
| SCHEMBL14678612 | 1.00 | TPSAB1 (0.46) | TPSAB1TPSD1TPSG1ERCC1ERCC4 | |
| SCHEMBL38339 | 1.00 | TPSAB1 (0.46) | TPSAB1TPSD1TPSG1ERCC1ERCC4 | |
| SCHEMBL38412 | 0.92 | ERCC1 (0.44) | TPSAB1TPSD1TPSG1ERCC1ERCC4 | |
| SCHEMBL38431 | 0.92 | ERCC1 (0.46) | TPSAB1TPSD1TPSG1ERCC1ERCC4 | |
| SCHEMBL38359 | 0.89 | ERCC1 (0.53) | TPSAB1TPSD1TPSG1ERCC1ERCC4 | |
| SCHEMBL38878 | 0.89 | ERCC1 (0.53) | TPSAB1TPSD1TPSG1ERCC1ERCC4 | |
| SCHEMBL41877 | 0.89 | ACHE (0.52) | TPSAB1TPSD1TPSG1ERCC1ERCC4 | |
| SCHEMBL41878 | 0.89 | ACHE (0.52) | TPSAB1TPSD1TPSG1ERCC1ERCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367835-B2 | Cyclic amine-1-carboxylic acid ester derivative and pharmaceutical composition containing the same | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20120028937-A1 | CYCLIC AMINE-1-CARBOXYLIC ACID ESTER DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028937-A1 | CYCLIC AMINE-1-CARBOXYLIC ACID ESTER DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | HRH3, ARG1, CNR1 | TPSAB1 2026/4885TPSD1 1801/4885TPSG1 4035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.