Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | PAM | P19021 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 3/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3833050 | 0.98 | DGKA (0.47) | DGKAPAMCYP1A2PRKCATSHR | |
| SCHEMBL3835097 | 0.92 | TSHR (0.45) | PAMTSHRALDH1A1LMNATDP1 | |
| SCHEMBL3836339 | 0.92 | TSHR (0.52) | DGKAPAMPRKCATSHRALDH1A1 | |
| Bis(Pivaloyloxymethyl) Succinate SCHEMBL3123390 | 0.91 | PRKCA (0.41) | DGKACYP1A2PRKCATSHRMAPT | |
| SCHEMBL7326020 | 0.90 | CYP1A2 (0.50) | DGKAPAMCYP1A2PRKCATSHR | |
| SCHEMBL3829281 | 0.90 | TSHR (0.50) | DGKAPAMPRKCATSHRALDH1A1 | |
| SCHEMBL25635496 | 0.90 | DGKA (0.60) | DGKAPAMPRKCATSHRMAPT | |
| SCHEMBL7326011 | 0.90 | DGKA (0.37) | DGKAPAMCYP1A2PRKCATSHR | |
| SCHEMBL3835787 | 0.90 | TSHR (0.50) | DGKAPAMPRKCATSHRALDH1A1 | |
| SCHEMBL3835714 | 0.90 | PAM (0.46) | PAMTSHRALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448508-B1 | DOUBLE ESTERS | DRUG DISCOVERY LAB AS (NO) | 2009-09-23 | — | — | EP | disclosed |
| EP-1448508-A1 | DOUBLE ESTERS | Photocure ASA (NO) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003045893-A1 | DOUBLE ESTERS | PHOTOCURE ASA (NO) | 2003-06-05 | — | — | WO | disclosed |