SCHEMBL3835375

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3831017	0.95	NAMPT (0.56)	NAMPTHDAC1HDAC6TRPV1ROCK1
	SCHEMBL3234596	0.90	NAMPT (0.45)	NAMPTHDAC1HDAC6TRPV1HDAC3
	SCHEMBL2477923	0.86	HDAC1 (0.54)	NAMPTHDAC1HDAC6HDAC3HDAC2
	SCHEMBL3834424	0.86	HDAC1 (0.54)	HDAC1HDAC6HDAC3HDAC2HDAC4
	SCHEMBL2471370	0.86	HDAC1 (0.53)	HDAC1HDAC6HDAC3HDAC2HDAC4
	SCHEMBL3835188	0.86	HDAC1 (0.55)	HDAC1HDAC6HDAC3HDAC2HDAC4
	SCHEMBL2476756	0.86	HDAC1 (0.53)	HDAC1HDAC6HDAC3HDAC2HDAC4
	SCHEMBL3832709	0.86	USP2 (0.55)	NAMPT
	SCHEMBL2470974	0.85	HDAC1 (0.53)	NAMPTHDAC1HDAC6TRPV1HDAC3
	SCHEMBL3225598	0.85	NAMPT (0.46)	NAMPTHDAC1HDAC3HDAC2ROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.