Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.68 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.68 |
| ▸ | HTR2B | P41595 | 1/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11602712 | 0.94 | LMNA (0.59) | LMNACYP3A4MAPTMEN1NR1I2 | |
| Water SCHEMBL11089583 | 0.92 | LMNA (0.57) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL15154872 | 0.84 | LMNA (0.77) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL2457396 | 0.83 | LMNA (0.70) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL7588539 | 0.83 | LMNA (0.70) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL3665313 | 0.83 | KMT2A (0.74) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL168816 | 0.83 | KMT2A (0.74) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL8800133 | 0.83 | LMNA (0.74) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL527254 | 0.83 | KMT2A (0.74) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL112985 | 0.83 | KMT2A (0.74) | LMNACYP3A4MAPTMEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445630-B2 | Polymers | BASF SE (DE) | 2013-05-21 | — | — | US | disclosed |
| US-8445630-B2 | Polymers | BASF SE (DE) | 2013-05-21 | — | — | US | disclosed |
| US-8445630-B2 | Polymers | BASF SE (DE) | 2013-05-21 | — | — | US | disclosed |
| EP-1858976-B1 | NOVEL POLYMERS | BASF SE (DE) | 2009-10-14 | — | — | EP | disclosed |
| EP-1858976-B1 | NOVEL POLYMERS | BASF SE (DE) | 2009-10-14 | — | — | EP | disclosed |
| US-20090105447-A1 | Novel Polymers | UDC IRELAND LIMITED (IE) | 2009-04-23 | — | — | US | disclosed |
| US-20090105447-A1 | Novel Polymers | UDC IRELAND LIMITED (IE) | 2009-04-23 | — | — | US | disclosed |
| US-20090105447-A1 | Novel Polymers | UDC IRELAND LIMITED (IE) | 2009-04-23 | — | — | US | disclosed |
| EP-1858976-A1 | NOVEL POLYMERS | Ciba Specialty Chemicals Holding Inc. (CH) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006097419-A1 | NOVEL POLYMERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105447-A1 | Novel Polymers | PLEC, VIM, PUF60 | LMNA 2836/4885CYP3A4 2377/4885MAPT 123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.