Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL385618 | 0.71 | PARP1 (0.41) | ALDH1A1HSD17B10HTTPARP1KMT2A | |
| SCHEMBL2557 | 0.66 | — | — | |
| SCHEMBL233601 | 0.64 | CA12 (0.43) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL386239 | 0.62 | PLAUR (0.44) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6538412 | 0.62 | KDM4E (0.34) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4466423 | 0.62 | ALDH1A1 (0.35) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9900685 | 0.61 | BRD4 (0.48) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL269768 | 0.61 | KDM4E (0.48) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL586416 | 0.61 | PLAUR (0.47) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11785225 | 0.61 | ALDH1A1 (0.38) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2189 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112969504-B | Compounds for inhibiting alpha 4 beta 7 integrin | 吉利德科学公司 | 2024-04-09 | — | — | CN | claimed |
| WO-2024037520-A1 | AMIDE COMPOUND, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 中国科学院上海药物研究所 | 2024-02-22 | — | — | WO | claimed |
| CN-112368289-B | C26-linked rapamycin analogues as MTOR inhibitors | 锐新医药公司 | 2024-02-20 | — | — | CN | claimed |
| WO-2024015569-A2 | SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION | JNANA THERAPEUTICS INC. (US) | 2024-01-18 | — | — | WO | claimed |
| WO-2024015574-A1 | SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION | JNANA THERAPEUTICS INC. (US) | 2024-01-18 | — | — | WO | claimed |
| WO-2023217906-A1 | PYRROLIDINONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-16 | — | — | WO | claimed |
| CN-116621833-A | KRAS G12C inhibitors and methods of use thereof | 美国安进公司 | 2023-08-22 | — | — | CN | claimed |
| WO-2023122267-A2 | SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION | JNANA THERAPEUTICS INC. (US) | 2023-06-29 | — | — | WO | claimed |
| CN-114957221-B | Quinoxaline derivative, and preparation method and application thereof | 广西师范大学 | 2023-05-12 | — | — | CN | claimed |
| US-20220393118-A1 | TETRADENTATE LIGANDS, GOLD(III) COMPLEXES, PREPARATION METHOD AND USE THEREOF | CHE, CHI MING (CN) | 2022-12-08 | — | — | US | claimed |
| EP-0132818-B1 | ISOINDOLINE PIGMENTS HAVING A STRONG COLOURING CAPACITY, THEIR PREPARATION AND THEIR USE | BASF Aktiengesellschaft (DE) | 1986-12-30 | — | — | EP | claimed |
| WO-1986006717-A1 | 3-AMINOPROPYLOXYPHENYL DERIVATIVES THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LOUIS WILLIAM JOHN (AU) | 1986-11-20 | — | — | WO | claimed |
| US-4599113-A | FINISHES, INKS | BASF AKTIENGESELLSCHAFT (DE) | 1986-07-08 | — | — | US | claimed |
| EP-0132818-A1 | Isoindoline pigments having a strong colouring capacity, their preparation and their use | BASF Aktiengesellschaft (DE) | 1985-02-13 | — | — | EP | claimed |
| US-4367173-A | POLYVINYL CHLORIDE, POLYETHYLENE | BASF AKTIENGESELLSCHAFT (DE) | 1983-01-04 | — | — | US | claimed |
| US-4316013-A | DISPERSE DYES | EASTMAN KODAK COMPANY (US) | 1982-02-16 | — | — | US | claimed |
| US-4314938-A | Iminoisoindolinone pigments containing phenylazoacetoacetyl-aminophenylene groups | CIBA-GEIGY CORPORATION (US) | 1982-02-09 | — | — | US | claimed |
| US-4312985-A | COLORFAST YELLOW AND ORANGE DYES FOR POLYESTERS AND CELLULOSE ACETATES | EASTMAN KODAK COMPANY (US) | 1982-01-26 | — | — | US | claimed |
| US-4166117-A | HYPOTENSIVES | SCIENCE UNION ET CIE (FR) | 1979-08-28 | — | — | US | claimed |
| US-4042577-A | POLYESTERS, POLYAMIDES, CELLULOSE ACETATES | SANDOZ LTD. (CH) | 1977-08-16 | — | — | US | claimed |