Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3834979 | 0.79 | KDR (0.34) | — | |
| SCHEMBL3835080 | 0.79 | AURKA (0.31) | — | |
| SCHEMBL3836696 | 0.75 | CLK4 (0.32) | — | |
| SCHEMBL3835834 | 0.75 | PTGS1 (0.35) | PARP1 | |
| SCHEMBL3834573 | 0.74 | PIK3CD (0.31) | — | |
| SCHEMBL3835406 | 0.72 | PARP1 (0.45) | PARP1 | |
| SCHEMBL3839267 | 0.72 | PIK3CD (0.32) | — | |
| SCHEMBL3835796 | 0.72 | MAP3K9 (0.38) | — | |
| SCHEMBL3840001 | 0.71 | PARP10 (0.36) | PARP1 | |
| SCHEMBL3835512 | 0.71 | KDR (0.41) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108642-A1 | JAK INHIBITOR | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-10-14 | — | — | EP | disclosed |