SCHEMBL383672

SCHEMBL383672

Cc1ccc([PH3+])c(C)c1C.F[B-](F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30
TSHR P16473 1/20 0.30
TDP2 O95551 1/20 0.30
NSD2 O96028 1/20 0.30
HSP90AA1 P07900 1/20 0.30
PAX8 Q06710 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10451668 0.78 TRPA1 (0.41) CYP1A2CYP2A6TSHR
SCHEMBL37955 0.71 TSHR (0.45) CYP1A2CYP2A6TSHRTDP2NSD2
SCHEMBL5494672 0.71 TSHR (0.45) CYP1A2CYP2A6TSHRTDP2NSD2
SCHEMBL384000 0.70 CYP1A2 (0.30) CYP1A2CYP2A6TSHRTDP2NSD2
SCHEMBL10346182 0.67 TSHR (0.43) CYP1A2CYP2A6TSHRTDP2NSD2
SCHEMBL5181689 0.67 TSHR (0.43) CYP1A2CYP2A6TSHRTDP2NSD2
SCHEMBL27478113 0.67 TSHR (0.43) CYP1A2CYP2A6TSHRTDP2NSD2
Ammonia Solution, Strong SCHEMBL27674355 0.67 TSHR (0.43) CYP1A2CYP2A6TSHRTDP2NSD2
SCHEMBL27731752 0.67 TSHR (0.43) CYP1A2CYP2A6TSHRTDP2NSD2
Methane SCHEMBL28022182 0.67 TSHR (0.43) CYP1A2CYP2A6TSHRTDP2NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2718448-A2 METHODS FOR TREATING LIGNOCELLULOSIC MATERIAL Syngenta Participations AG (CH) 2014-04-16 EP disclosed
WO-2012168410-A2 METHODS FOR TREATING LIGNOCELLULOSIC MATERIAL SYNGENTA PARTICIPATIONS AG (CH) 2012-12-13 WO disclosed
EP-2439208-A1 Method of preparing organometallic compounds Rohm and Haas Company (US) 2012-04-11 EP disclosed
US-8101787-B2 Method of preparing organometallic compounds ROHM AND HAAS COMPANY (US) 2012-01-24 US disclosed
EP-2359923-A1 Method of preparing organometallic compounds Rohm and Haas Company (US) 2011-08-24 EP disclosed
EP-2359922-A1 Method of preparing organometallic compounds Rohm and Haas Company (US) 2011-08-24 EP disclosed
US-20110172452-A1 Method of Preparing Organometallic Compounds ROHM AND HAAS COMPANY (US) 2011-07-14 US disclosed
US-7939684-B2 Method of preparing organometallic compounds ROHM AND HAAS COMPANY (US) 2011-05-10 US disclosed
US-7919638-B2 Method of preparing organometallic compounds ROHM AND HAAS COMPANY (US) 2011-04-05 US disclosed
US-20100185003-A1 Method of Preparing Organometallic Compounds ROHM AND HAAS COMPANY (US) 2010-07-22 US disclosed
US-20100185002-A1 Method of Preparing Organometallic Compounds ROHM AND HAAS COMPANY (US) 2010-07-22 US disclosed
US-7659414-B2 Method of preparing organometallic compounds ROHM AND HAAS COMPANY (US) 2010-02-09 US disclosed
EP-2020258-A2 Method Of Preparing Organometallic Compounds Rohm and Haas Company (US) 2009-02-04 EP disclosed
US-20090023940-A1 Method of preparing organometallic compounds ROHM AND HAAS COMPANY 2009-01-22 US disclosed