Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.36 |
| ▸ | PPARG | P37231 | 7/20 | 0.36 |
| ▸ | PPARD | Q03181 | 7/20 | 0.36 |
| ▸ | PPARA | Q07869 | 7/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4442105 | 0.87 | FFAR4 (0.55) | FFAR4FFAR1MAPTMAPK1GPR84 | |
| SCHEMBL5570015 | 0.83 | FFAR1 (0.42) | FFAR4FFAR1MAPTMAPK1NFKB1 | |
| SCHEMBL7612157 | 0.79 | MAPT (0.60) | FFAR4FFAR1MAPTMAPK1ALDH1A1 | |
| SCHEMBL28452236 | 0.79 | MAPT (0.60) | FFAR4FFAR1MAPTMAPK1ALDH1A1 | |
| SCHEMBL8516654 | 0.78 | LMNA (0.41) | FFAR4FFAR1MAPTMAPK1NFKB1 | |
| SCHEMBL2728235 | 0.77 | FFAR4 (0.58) | FFAR4FFAR1MAPTMAPK1AKR1B1 | |
| SCHEMBL2729585 | 0.77 | FFAR4 (0.58) | FFAR4FFAR1MAPTMAPK1AKR1B1 | |
| SCHEMBL11151057 | 0.77 | FFAR4 (0.58) | FFAR4FFAR1MAPTMAPK1AKR1B1 | |
| SCHEMBL2729299 | 0.77 | FFAR4 (0.58) | FFAR4FFAR1MAPTMAPK1AKR1B1 | |
| SCHEMBL2730102 | 0.77 | FFAR4 (0.58) | FFAR4FFAR1MAPTMAPK1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313860-B1 | BUTINOL I ESTERASE | BASF SE (DE) | 2009-10-14 | — | — | EP | disclosed |