SCHEMBL5570015

SCHEMBL5570015

O=C(O)CCCCC(=O)OC(CCCO)C(O)CO

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.42
FFAR4 Q5NUL3 2/20 0.42
GPR84 Q9NQS5 1/20 0.42
CAMK2A Q9UQM7 1/20 0.41
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.37
PTPN1 P18031 1/20 0.36
LMNA P02545 2/20 0.35
TSHR P16473 2/20 0.35
NFKB1 P19838 1/20 0.34
PMP22 Q01453 1/20 0.34
PRKCA P17252 1/20 0.33
PRKCE Q02156 1/20 0.33
PRKCQ Q04759 1/20 0.33
PRKCD Q05655 1/20 0.33
GSTK1 Q9Y2Q3 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL754093 0.93 MAPT (0.41) MAPTMAPK1PTPN1LMNAPRKCA
SCHEMBL1771656 0.87 FFAR1 (0.42) FFAR1FFAR4GPR84CAMK2AMAPT
SCHEMBL8516654 0.86 LMNA (0.41) FFAR1FFAR4GPR84CAMK2AMAPT
SCHEMBL4442105 0.85 FFAR4 (0.55) FFAR1FFAR4GPR84MAPTMAPK1
SCHEMBL3836893 0.83 FFAR4 (0.40) FFAR1FFAR4GPR84MAPTMAPK1
SCHEMBL2457362 0.80 MAPT (0.55) MAPTMAPK1PTPN1LMNAPRKCA
SCHEMBL8523522 0.80 MAPT (0.41) MAPTMAPK1PTPN1LMNAPRKCA
SCHEMBL17331075 0.79 CAMK2A (0.38) FFAR1FFAR4GPR84CAMK2AMAPT
SCHEMBL9009030 0.78 FFAR1 (0.52) FFAR1FFAR4GPR84CAMK2AMAPT
SCHEMBL28452236 0.77 MAPT (0.60) FFAR1FFAR4MAPTMAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4321173-A Method for the preparation of finely dispersed polyurethane ureas FIRMA CARL FREUDENBERG (DE) 1982-03-23 US claimed
US-4310373-A Method for heat-sealing textile materials with polyurethane adhesives FIRMA CARL FREUDENBERG (DE) 1982-01-12 US claimed
US-4307004-A FOR BONDING TEXTILES FIRMA CARL FREUDENBERG (DE) 1981-12-22 US claimed
US-4273911-A Method for the manufacture of low-melting polyurethanes having improved strength properties using a mixture of a polydiol having a molecular weight between 500 and 5,000 and a mixture of at least three diols FIRMA CARL FREUDENBERG (DE) 1981-06-16 US claimed
US-20070149751-A1 Bulk manufacturing of supramolecular polymer forming polymer LINDSAY CHRISTOPHER I 2007-06-28 US disclosed
US-4321173-A Method for the preparation of finely dispersed polyurethane ureas FIRMA CARL FREUDENBERG (DE) 1982-03-23 US disclosed
US-4310373-A Method for heat-sealing textile materials with polyurethane adhesives FIRMA CARL FREUDENBERG (DE) 1982-01-12 US disclosed
US-4307004-A FOR BONDING TEXTILES FIRMA CARL FREUDENBERG (DE) 1981-12-22 US disclosed
US-4273911-A Method for the manufacture of low-melting polyurethanes having improved strength properties using a mixture of a polydiol having a molecular weight between 500 and 5,000 and a mixture of at least three diols FIRMA CARL FREUDENBERG (DE) 1981-06-16 US disclosed