Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1771656 | 0.86 | FFAR1 (0.42) | LMNAMAPTMAPK1TSHRNFKB1 | |
| SCHEMBL5570015 | 0.86 | FFAR1 (0.42) | LMNAMAPTMAPK1TSHRNFKB1 | |
| SCHEMBL22579234 | 0.82 | MAPT (0.64) | LMNAMAPTMAPK1PRKCAPRKCE | |
| SCHEMBL30932019 | 0.82 | MAPT (0.64) | LMNAMAPTMAPK1PRKCAPRKCE | |
| SCHEMBL4442105 | 0.81 | FFAR4 (0.55) | LMNAMAPTMAPK1TSHRGPR84 | |
| SCHEMBL17509581 | 0.79 | MAPT (0.42) | LMNAMAPTMAPK1TSHRNFKB1 | |
| SCHEMBL3836893 | 0.78 | FFAR4 (0.40) | MAPTMAPK1TSHRNFKB1GPR84 | |
| SCHEMBL5428969 | 0.78 | GPR84 (0.34) | LMNAMAPTMAPK1TSHRNFKB1 | |
| SCHEMBL754093 | 0.78 | MAPT (0.41) | LMNAMAPTMAPK1PRKCAPRKCE | |
| SCHEMBL8523522 | 0.78 | MAPT (0.41) | LMNAMAPTMAPK1PRKCAPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729483-B1 | LOW FOGGING POLYESTER POLYURETHANE FOAMS | BAXENDEN CHEM (GB) | 1999-01-27 | — | — | EP | disclosed |
| US-5712320-A | Low fogging polyester polyurethane foams | CROMPTON COLORS INCORPORATED | 1998-01-27 | — | — | US | disclosed |
| EP-0729483-A1 | LOW FOGGING POLYESTER POLYURETHANE FOAMS | BAXENDEN CHEMICALS LTD (GB) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995014050-A1 | LOW FOGGING POLYESTER POLYURETHANE FOAMS | BAXENDEN CHEMICALS LIMITED (GB) | 1995-05-26 | — | — | WO | disclosed |