Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3839762 | 0.99 | HRH3 (0.48) | HRH3ALDH1A1ACP1KAT2BMAPK1 | |
| SCHEMBL3837169 | 0.97 | ALDH1A1 (0.46) | HRH3ALDH1A1ACP1KAT2BMAPK1 | |
| SCHEMBL1842899 | 0.92 | ALDH1A1 (0.53) | HRH3ALDH1A1ACP1KAT2BHTT | |
| SCHEMBL1843595 | 0.91 | ALDH1A1 (0.51) | HRH3ALDH1A1ACP1KAT2BHTT | |
| SCHEMBL1844288 | 0.82 | KAT2B (0.49) | ALDH1A1KAT2BHTT | |
| SCHEMBL3839737 | 0.82 | MAPT (0.40) | ALDH1A1HTTKDM4ELMNAPOLB | |
| SCHEMBL3839641 | 0.81 | HTT (0.47) | ALDH1A1MAPK1HTTKDM4ELMNA | |
| SCHEMBL3839943 | 0.81 | GSTM2 (0.40) | ALDH1A1MAPK1HTTKDM4ELMNA | |
| SCHEMBL5526719 | 0.81 | HRH3 (0.46) | HRH3ACP1KAT2B | |
| SCHEMBL13646825 | 0.80 | ALDH1A1 (0.34) | ALDH1A1MAPK1HTTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1792903-B1 | Composition for the dyeing of keratin fibres comprising at least one cationic 3-amino-pyrazolopyridine derivative | OREAL (FR) | 2009-10-14 | — | — | EP | disclosed |
| EP-1792903-B1 | Composition for the dyeing of keratin fibres comprising at least one cationic 3-amino-pyrazolopyridine derivative | OREAL (FR) | 2009-10-14 | — | — | EP | disclosed |
| US-7578855-B2 | Composition for dyeing keratin fibers comprising at least one cationic 3-amino-pyrazolopyridine derivative, and methods of use thereof | L'ORéAL S.A. (FR) | 2009-08-25 | — | — | US | disclosed |
| US-7578855-B2 | Composition for dyeing keratin fibers comprising at least one cationic 3-amino-pyrazolopyridine derivative, and methods of use thereof | L'ORéAL S.A. (FR) | 2009-08-25 | — | — | US | disclosed |
| US-7578855-B2 | Composition for dyeing keratin fibers comprising at least one cationic 3-amino-pyrazolopyridine derivative, and methods of use thereof | L'ORéAL S.A. (FR) | 2009-08-25 | — | — | US | disclosed |
| US-20070136959-A1 | Composition for dyeing keratin fibers comprising at least one cationic 3-amino-pyrazolopyridine derivative, and methods of use thereof | L'OREAL S.A. (FR) | 2007-06-21 | — | — | US | disclosed |
| US-20070136959-A1 | Composition for dyeing keratin fibers comprising at least one cationic 3-amino-pyrazolopyridine derivative, and methods of use thereof | L'OREAL S.A. (FR) | 2007-06-21 | — | — | US | disclosed |
| US-20070136959-A1 | Composition for dyeing keratin fibers comprising at least one cationic 3-amino-pyrazolopyridine derivative, and methods of use thereof | L'OREAL S.A. (FR) | 2007-06-21 | — | — | US | disclosed |
| EP-1792903-A1 | Composition for the dyeing of keratin fibres comprising at least one cationic 3-amino-pyrazolopyridine derivative | L'OREAL (FR) | 2007-06-06 | — | — | EP | disclosed |
| EP-1792903-A1 | Composition for the dyeing of keratin fibres comprising at least one cationic 3-amino-pyrazolopyridine derivative | L'OREAL (FR) | 2007-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070136959-A1 | Composition for dyeing keratin fibers comprising at least one cationic 3-amino-pyrazolopyridine derivative, and methods of use thereof | KRT18, COX5A, PNPO | HRH3 1616/4885ALDH1A1 264/4885ACP1 190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.