Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.44 |
| ▸ | TUBB | P07437 | 3/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL918688 | 0.84 | AHR (0.55) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL918690 | 0.84 | AHR (0.55) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL20289186 | 0.77 | KDM4E (0.49) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL5960472 | 0.76 | KMT2A (0.51) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL718479 | 0.76 | KMT2A (0.77) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL718478 | 0.76 | KMT2A (0.77) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL4982103 | 0.74 | NFE2L2 (0.61) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL4982109 | 0.74 | NFE2L2 (0.61) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL8927316 | 0.74 | KMT2A (0.42) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL8210257 | 0.74 | KMT2A (0.42) | KMT2AKDM4EMAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1248774-B1 | POLYHYDROXYSTILBENES AND STILBENE OXIDES AS ANTIPSORIATIC AGENTS AND PROTEIN KINASE INHIBITORS | WELICHEM BIOTECH INC (CA) | 2009-10-07 | — | — | EP | claimed |