Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718479 | 0.80 | KMT2A (0.77) | KMT2ACYP3A4MAPTTP53KDM4E | |
| SCHEMBL718478 | 0.80 | KMT2A (0.77) | KMT2ACYP3A4MAPTTP53KDM4E | |
| SCHEMBL5610949 | 0.78 | TUBB1 (0.50) | KMT2ACYP3A4MAPTTP53KDM4E | |
| SCHEMBL5610950 | 0.78 | TUBB1 (0.50) | KMT2ACYP3A4MAPTTP53KDM4E | |
| SCHEMBL716755 | 0.76 | KMT2A (0.71) | KMT2ACYP3A4MAPTTP53KDM4E | |
| SCHEMBL716756 | 0.76 | KMT2A (0.71) | KMT2ACYP3A4MAPTTP53KDM4E | |
| SCHEMBL27677458 | 0.76 | PTPN1 (0.76) | KMT2ACYP3A4MAPTTP53KDM4E | |
| SCHEMBL3837232 | 0.76 | KMT2A (0.47) | KMT2ACYP3A4MAPTTP53KDM4E | |
| SCHEMBL716895 | 0.75 | KMT2A (0.60) | KMT2ACYP3A4MAPTTP53KDM4E | |
| SCHEMBL716894 | 0.75 | KMT2A (0.60) | KMT2ACYP3A4MAPTTP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006004722-A2 | COMPOSITIONS AND METHODS FOR SELECTIVELY ACTIVATING HUMAN SIRTUINS | BIOMOL RESEARCH LABORATORIES, INC. (US) | 2006-01-12 | — | — | WO | claimed |