Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GGT1 | P19440 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4982109 | 1.00 | NFE2L2 (0.61) | NFE2L2TRPA1KMT2AMEN1NPC1 | |
| SCHEMBL1603612 | 0.91 | MEN1 (0.60) | NFE2L2TRPA1KMT2AMEN1NPC1 | |
| SCHEMBL16915428 | 0.87 | KDM4E (0.51) | NFE2L2TRPA1KMT2AMEN1NPC1 | |
| SCHEMBL16915429 | 0.87 | KDM4E (0.51) | NFE2L2TRPA1KMT2AMEN1NPC1 | |
| SCHEMBL1603616 | 0.87 | NFE2L2 (0.60) | NFE2L2TRPA1KMT2AMEN1NPC1 | |
| SCHEMBL11505719 | 0.86 | NFE2L2 (0.72) | NFE2L2TRPA1KMT2AMEN1NPC1 | |
| SCHEMBL9244563 | 0.86 | NFE2L2 (0.59) | NFE2L2TRPA1KMT2ANPC1RAB9A | |
| SCHEMBL29733304 | 0.85 | NFE2L2 (0.56) | NFE2L2TRPA1KMT2AMEN1NPC1 | |
| SCHEMBL16915445 | 0.84 | CYP11B1 (0.50) | KMT2AMEN1NPC1RAB9AHSP90AA1 | |
| SCHEMBL16915447 | 0.84 | CYP11B1 (0.50) | KMT2AMEN1NPC1RAB9AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120172340-A1 | Compositions and Methods for Selectively Activating Human Sirtuins | BIOMOL INTERNATIONAL L.P. (US) | 2012-07-05 | — | — | US | claimed |
| CN-104994831-A | Use of a resveratrol derivative for skin whitening | KYUNGPOOK NAT UNIV IND ACAD | 2015-10-21 | — | — | CN | disclosed |
| US-20120172340-A1 | Compositions and Methods for Selectively Activating Human Sirtuins | BIOMOL INTERNATIONAL L.P. (US) | 2012-07-05 | — | — | US | disclosed |
| EP-1984317-A1 | NOVEL NUTRACEUTICAL AND PHARMACEUTICAL COMPOSITIONS AND USE THEREOF FOR THE TREATMENT, CO-TREATMENT OR PREVENTION OF INFLAMMATORY DISORDERS | DSMIP Assets B.V. (NL) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007093387-A1 | NOVEL NUTRACEUTICAL AND PHARMACEUTICAL COMPOSITIONS AND USE THEREOF FOR THE TREATMENT, CO-TREATMENT OR PREVENTION OF INFLAMMATORY DISORDERS | DSM IP ASSETS B.V. (NL) | 2007-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172340-A1 | Compositions and Methods for Selectively Activating Human Sirtuins | SIRT1, SIRT7, SIRT5 | NFE2L2 2187/4885TRPA1 4798/4885KMT2A 635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.