Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3842956 | 0.94 | ADORA3 (0.36) | ADORA3ADORA2AADORA2BKDM4EHSD17B10 | |
| SCHEMBL1919622 | 0.89 | ALDH1A1 (0.38) | ADORA3ADORA2AADORA2BRIPK1ADORA1 | |
| SCHEMBL17797195 | 0.87 | ADORA3 (0.37) | ADORA3ADORA2AADORA2BRIPK1ADORA1 | |
| SCHEMBL3841889 | 0.87 | ALOX5AP (0.39) | ADORA3ADORA2AADORA2BRIPK1ADORA1 | |
| SCHEMBL3841828 | 0.85 | RIPK1 (0.36) | ADORA3ADORA2AADORA2BRIPK1ADORA1 | |
| SCHEMBL3837173 | 0.84 | ALOX5AP (0.34) | KDM4EHSD17B10 | |
| SCHEMBL28792444 | 0.84 | RIPK1 (0.35) | RIPK1KDM4EHSD17B10 | |
| SCHEMBL3839336 | 0.82 | KDM4E (0.43) | ADORA3ADORA2ARIPK1KDM4EHSD17B10 | |
| SCHEMBL3839254 | 0.81 | KDM4E (0.36) | ADORA3ADORA2ARIPK1KDM4EHSD17B10 | |
| SCHEMBL3859281 | 0.81 | HSD17B10 (0.38) | ADORA3ADORA2AADORA2BKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2060566-B1 | Poly-substituted aryls | DOW AGROSCIENCES LLC (US) | 2016-06-08 | — | — | EP | claimed |
| EP-2060566-B1 | Poly-substituted aryls | DOW AGROSCIENCES LLC (US) | 2016-06-08 | — | — | EP | disclosed |
| EP-1973881-B1 | 6-(POLY-SUBSTITUTED ARYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-10-28 | — | — | EP | disclosed |
| EP-2060566-A1 | Poly-substituted aryls | Dow AgroSciences LLC (US) | 2009-05-20 | — | — | EP | disclosed |
| US-7498468-B2 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2009-03-03 | — | — | US | disclosed |
| EP-1973881-A2 | 6-(POLY-SUBSTITUTED ARYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | Dow Agrosciences LLC (US) | 2008-10-01 | — | — | EP | disclosed |
| US-20080051596-A1 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2008-02-28 | — | — | US | disclosed |
| US-20080045734-A1 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2008-02-21 | — | — | US | disclosed |
| US-7314849-B2 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2008-01-01 | — | — | US | disclosed |
| US-20070179060-A1 | 6-(Poly-substituted aryl)-4-aminopicolinates and their use as herbicides | CORTEVA AGRISCIENCE LLC | 2007-08-02 | — | — | US | disclosed |
| WO-2007082098-A2 | 6-(POLY-SUBSTITUTED ARYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045734-A1 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | AAAS, DDT, AADAC | ADORA3 378/4885ADORA2A 2184/4885ADORA2B 1952/4885 |
| US-20070179060-A1 | 6-(Poly-substituted aryl)-4-aminopicolinates and their use as herbicides | AAAS, DDT, AADAC | ADORA3 378/4885ADORA2A 2184/4885ADORA2B 1952/4885 |
| US-20080051596-A1 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | AAAS, DDT, AADAC | ADORA3 378/4885ADORA2A 2184/4885ADORA2B 1952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.