SCHEMBL3837469

SCHEMBL3837469

NC(=O)c1cccc(Oc2ccc(F)c(C(F)(F)F)c2)n1

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 11/20 0.58
MAPT P10636 1/20 0.49
KDR P35968 4/20 0.46
FLT1 P17948 2/20 0.46
FLT4 P35916 2/20 0.46
HSD17B14 Q9BPX1 1/20 0.46
OPRM1 P35372 1/20 0.45
F10 P00742 1/20 0.44
CDK8 P49336 1/20 0.43
FPR2 P25090 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8569584 0.81 MAPT (0.73) SCN9AMAPTOPRM1F10
SCHEMBL7108378 0.75 MAPT (0.49) SCN9AMAPTKDRCDK8
SCHEMBL7108276 0.75 MAPT (0.52) SCN9AMAPTKDRHSD17B14F10
SCHEMBL7110923 0.75 MAPT (0.49) SCN9AMAPTHSD17B14F10
SCHEMBL16129924 0.74 SCN9A (1.00) SCN9A
SCHEMBL8067985 0.74 MAPT (0.51) SCN9AMAPTKDRFLT1FLT4
SCHEMBL8072818 0.74 MAPT (0.48) SCN9AMAPTKDRFLT1FLT4
SCHEMBL725893 0.73 OPRM1 (0.62) SCN9AMAPTHSD17B14OPRM1F10
SCHEMBL7111276 0.73 MAPT (0.53) SCN9AMAPT
SCHEMBL12095228 0.73 HTR2A (0.41) KDRFLT1FLT4HSD17B14OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1297113-B1 CYANOBACTERIAL NUCLEIC ACID FRAGMENTS ENCODING PROTEINS USEFUL FOR CONTROLLING PLANT TRAITS VIA NUCLEAR OR PLASTOME TRANSFORMATION BASF SE (DE) 2009-10-28 EP claimed
US-7285701-B2 Cyanobacterial nucleic acid fragments encoding proteins useful for controlling plant traits via nuclear or plastome transformation BASF PLANT SCIENCE GMBH (US) 2007-10-23 US claimed
US-20060143730-A1 Cyanobacterial nucleic acid fragments encoding proteins useful for controlling plant traits via nuclear or plastome transformation BASF CORPORATION (US) 2006-06-29 US claimed
EP-1297113-B1 CYANOBACTERIAL NUCLEIC ACID FRAGMENTS ENCODING PROTEINS USEFUL FOR CONTROLLING PLANT TRAITS VIA NUCLEAR OR PLASTOME TRANSFORMATION BASF SE (DE) 2009-10-28 EP disclosed
EP-1297113-B1 CYANOBACTERIAL NUCLEIC ACID FRAGMENTS ENCODING PROTEINS USEFUL FOR CONTROLLING PLANT TRAITS VIA NUCLEAR OR PLASTOME TRANSFORMATION BASF SE (DE) 2009-10-28 EP disclosed
EP-2108694-A1 Cyanobacterial nucleic acid fragments encoding proteins useful for controlling plant traits via nuclear or plastome transformation BASF SE (DE) 2009-10-14 EP disclosed
US-7285701-B2 Cyanobacterial nucleic acid fragments encoding proteins useful for controlling plant traits via nuclear or plastome transformation BASF PLANT SCIENCE GMBH (US) 2007-10-23 US disclosed
US-7285701-B2 Cyanobacterial nucleic acid fragments encoding proteins useful for controlling plant traits via nuclear or plastome transformation BASF PLANT SCIENCE GMBH (US) 2007-10-23 US disclosed
US-7083967-B1 Cyanobacterial nucleic acid fragments encoding proteins useful for controlling plant traits via nuclear or plastome transformation BASF CORPORATION (US) 2006-08-01 US disclosed
US-20060143730-A1 Cyanobacterial nucleic acid fragments encoding proteins useful for controlling plant traits via nuclear or plastome transformation BASF CORPORATION (US) 2006-06-29 US disclosed
US-20060143730-A1 Cyanobacterial nucleic acid fragments encoding proteins useful for controlling plant traits via nuclear or plastome transformation BASF CORPORATION (US) 2006-06-29 US disclosed
EP-1297113-A4 CYANOBACTERIAL NUCLEIC ACID FRAGMENTS ENCODING PROTEINS USEFUL FOR CONTROLLING PLANT TRAITS VIA NUCLEAR OR PLASTOME TRANSFORMATION BASF AG (DE) 2005-04-20 EP disclosed
EP-1297113-A4 CYANOBACTERIAL NUCLEIC ACID FRAGMENTS ENCODING PROTEINS USEFUL FOR CONTROLLING PLANT TRAITS VIA NUCLEAR OR PLASTOME TRANSFORMATION BASF AG (DE) 2005-04-20 EP disclosed
EP-1297113-A2 CYANOBACTERIAL NUCLEIC ACID FRAGMENTS ENCODING PROTEINS USEFUL FOR CONTROLLING PLANT TRAITS VIA NUCLEAR OR PLASTOME TRANSFORMATION AMERICAN CYANAMID COMPANY (US) 2003-04-02 EP disclosed
EP-1297113-A2 CYANOBACTERIAL NUCLEIC ACID FRAGMENTS ENCODING PROTEINS USEFUL FOR CONTROLLING PLANT TRAITS VIA NUCLEAR OR PLASTOME TRANSFORMATION AMERICAN CYANAMID COMPANY (US) 2003-04-02 EP disclosed
WO-2002000915-A3 CYANOBACTERIAL NUCLEIC ACID FRAGMENTS ENCODING PROTEINS USEFUL FOR CONTROLLING PLANT TRAITS VIA NUCLEAR OR PLASTOME TRANSFORMATION AMERICAN CYANAMID CO (US) 2002-04-18 WO disclosed
WO-2002000915-A2 CYANOBACTERIAL NUCLEIC ACID FRAGMENTS ENCODING PROTEINS USEFUL FOR CONTROLLING PLANT TRAITS VIA NUCLEAR OR PLASTOME TRANSFORMATION BASF AKTIENGESELLSCHAFT (DE) 2002-01-03 WO disclosed
WO-2002000915-A2 CYANOBACTERIAL NUCLEIC ACID FRAGMENTS ENCODING PROTEINS USEFUL FOR CONTROLLING PLANT TRAITS VIA NUCLEAR OR PLASTOME TRANSFORMATION BASF AKTIENGESELLSCHAFT (DE) 2002-01-03 WO disclosed