SCHEMBL725893

SCHEMBL725893

NC(=O)c1cccc(Oc2ccccc2)n1

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.62
HSD17B14 Q9BPX1 1/20 0.53
F10 P00742 8/20 0.51
F2 P00734 6/20 0.51
PRSS1 P07477 1/20 0.51
PRSS2 P07478 1/20 0.51
PRSS3 P35030 1/20 0.51
ST14 Q9Y5Y6 1/20 0.51
PARP10 Q53GL7 1/20 0.49
KCNH2 Q12809 1/20 0.46
CTNNB1 P35222 1/20 0.46
MAPT P10636 1/20 0.45
PLA2G10 O15496 1/20 0.45
SCN9A Q15858 2/20 0.44
P2RX3 P56373 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30261671 0.87 OPRM1 (0.53) OPRM1HSD17B14F10F2PRSS1
SCHEMBL7110101 0.86 KDM4E (0.57) OPRM1HSD17B14F10F2PRSS1
SCHEMBL28252043 0.83 HSD17B14 (0.53) OPRM1HSD17B14F10F2PRSS1
SCHEMBL23188985 0.83 HSD17B14 (0.53) OPRM1HSD17B14F10F2PRSS1
SCHEMBL28748015 0.82 OPRM1 (0.65) OPRM1F10F2PRSS1PRSS2
SCHEMBL8068188 0.82 P2RX7 (0.53) OPRM1HSD17B14F10F2PRSS1
SCHEMBL3697994 0.82 OPRM1 (0.61) OPRM1F10F2PRSS1PRSS2
SCHEMBL3696055 0.81 OPRM1 (0.67) OPRM1F10F2PRSS1PRSS2
SCHEMBL8498266 0.80 F10 (0.48) OPRM1HSD17B14F10F2PARP10
SCHEMBL7608437 0.80 MAPT (0.67) OPRM1HSD17B14MAPTP2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4749647-B2 2011-08-17 JP claimed
EP-1464223-B1 Synergistic herbicidal mixtures BASF AG (DE) 2006-08-23 EP claimed
EP-1267612-B1 SYNERGISTIC HERBICIDAL MIXTURES BASF AG (DE) 2004-11-03 EP claimed
EP-1464223-A1 Synergistic herbicidal mixtures BASF AKTIENGESELLSCHAFT (DE) 2004-10-06 EP claimed
US-6645911-B2 Using a 6-phenoxypyridyl-2-yl carboxamide compound BASF AKTIENGESELLSCHAFT (DE) 2003-11-11 US claimed
JP-2003528893-A 2003-09-30 JP claimed
EP-1267612-A1 SYNERGISTIC HERBICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2003-01-02 EP claimed
US-20020028747-A1 Synergistic herbicidal mixtures BASF AKTIENGESELLSCHAFT (DE) 2002-03-07 US claimed
WO-2001074157-A2 SYNERGISTIC HERBICIDAL MIXTURES BASF AG (DE) 2001-10-11 WO claimed
CN-119528914-A Benzazepine ketone derivative and application thereof 杭州百诚医药科技股份有限公司 2025-02-28 CN disclosed
EP-3342771-B1 HETEROCYCLIC AMIDES AS KINASE INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2020-11-25 EP disclosed
EP-3375780-B1 HETEROCYCLIC AMIDES AS KINASE INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2020-06-03 EP disclosed
EP-3508484-A1 HETEROCYCLIC AMIDES AS KINASE INHIBITORS GlaxoSmithKline Intellectual Property Development Limited (GB) 2019-07-10 EP disclosed
EP-3342771-A1 HETEROCYCLIC AMIDES AS KINASE INHIBITORS GlaxoSmithKline Intellectual Property Development Ltd (GB) 2018-07-04 EP disclosed
WO-1999024427-A1 HERBICIDAL FURANYL- AND THIENYLOXYAZINES AMERICAN CYANAMID COMPANY (US) 1999-05-20 WO disclosed
US-5869426-A Herbicidal 6-thienyloxypyrid-2-carboxamides AMERICAN CYANAMID COMPANY (US) 1999-02-09 US disclosed
US-5707932-A PLANT GROWTH REGULATORS; PRE- AND POSTEMERGENCE AMERICAN CYANAMID COMPANY (US) 1998-01-13 US disclosed
EP-0665841-B1 HERBICIDAL PYRAZOLYLOXY-PICOLINAMIDES SHELL INT RESEARCH (NL) 1996-07-17 EP disclosed
US-5384305-A Plant growth regulators SHELL RESEARCH LIMITED (GB) 1995-01-24 US disclosed
EP-0488474-A1 Herbicidal carboxamide derivatives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-06-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020028747-A1 Synergistic herbicidal mixtures CACNA1F, THRA, CA5A OPRM1 1843/4885HSD17B14 2763/4885F10 4493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.