Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MITF | O75030 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | IGF1R | P08069 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4875943 | 0.99 | ALDH1A1 (0.60) | ALDH1A1LMNAKDM4EMITFSMN1; SMN2 | |
| SCHEMBL3837620 | 0.88 | HTR1A (0.67) | ALDH1A1LMNAKDM4EKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL4811673 | 0.87 | HTR1A (0.66) | ALDH1A1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL3838547 | 0.87 | SLC6A4 (0.60) | ALDH1A1KDM4EKMT2AMEN1GAA | |
| Hydrochloric Acid SCHEMBL3840088 | 0.86 | SLC6A4 (0.59) | ALDH1A1KDM4EMITFSMN1; SMN2KMT2A | |
| SCHEMBL4874455 | 0.86 | ALDH1A1 (0.76) | ALDH1A1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL3840479 | 0.84 | KDM4E (0.56) | ALDH1A1KDM4EKMT2AMEN1KDR | |
| Hydrochloric Acid SCHEMBL4873626 | 0.82 | KDM4E (0.55) | ALDH1A1KDM4EKMT2AMEN1KDR | |
| SCHEMBL3841498 | 0.81 | KMT2A (0.56) | ALDH1A1KDM4EKMT2AMEN1GAA | |
| SCHEMBL4471401 | 0.80 | KDM4E (0.74) | ALDH1A1LMNAKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1553092-B1 | ARALKYL FORMYL-ALKYL PIPERAZINE DERIVATIVES AND THEIR USES AS CEREBRAL NERVE PROTECTIVE AGENT | SHANGHAI INST PHARM INDUSTRY (CN) | 2009-11-04 | — | — | EP | claimed |