Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3837174 | 0.85 | KDR (0.34) | KDR | |
| SCHEMBL3837161 | 0.84 | KDR (0.39) | KDR | |
| SCHEMBL3837163 | 0.83 | KDR (0.35) | KDR | |
| SCHEMBL3836776 | 0.80 | AURKA (0.34) | KDRAURKA | |
| SCHEMBL3835406 | 0.79 | PARP1 (0.45) | — | |
| SCHEMBL3836958 | 0.77 | PARP1 (0.36) | — | |
| SCHEMBL3839251 | 0.77 | PARP1 (0.33) | — | |
| SCHEMBL3837257 | 0.76 | PDE3B (0.43) | KDRAURKA | |
| SCHEMBL3836956 | 0.75 | SLC2A1 (0.35) | — | |
| SCHEMBL3835742 | 0.74 | AURKA (0.37) | KDRAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108642-A1 | JAK INHIBITOR | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-10-14 | — | — | EP | disclosed |