Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3837163 | 0.89 | KDR (0.35) | KDR | |
| SCHEMBL3839331 | 0.85 | KDR (0.32) | KDR | |
| SCHEMBL3837161 | 0.82 | KDR (0.39) | KDR | |
| SCHEMBL3836776 | 0.77 | AURKA (0.34) | KDR | |
| SCHEMBL3836958 | 0.77 | PARP1 (0.36) | — | |
| SCHEMBL3837343 | 0.72 | L3MBTL1 (0.39) | — | |
| SCHEMBL3839269 | 0.71 | AR (0.31) | — | |
| SCHEMBL3834414 | 0.71 | PARP1 (0.48) | KDR | |
| SCHEMBL3835801 | 0.71 | ELANE (0.37) | KDR | |
| SCHEMBL3837642 | 0.71 | PARP1 (0.37) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108642-A1 | JAK INHIBITOR | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-10-14 | — | — | EP | disclosed |