Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.64 |
| ▸ | CTSL | P07711 | 17/20 | 0.64 |
| ▸ | CTSK | P43235 | 15/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3837674 | 0.99 | CTSS (0.64) | CTSSCTSLCTSK | |
| SCHEMBL8288964 | 0.88 | CTSS (0.81) | CTSSCTSLCTSK | |
| SCHEMBL8290915 | 0.87 | CTSS (0.81) | CTSSCTSLCTSK | |
| SCHEMBL3840386 | 0.86 | CTSS (0.72) | CTSSCTSLCTSK | |
| SCHEMBL3840211 | 0.80 | CTSS (0.50) | CTSSCTSLCTSK | |
| SCHEMBL3835915 | 0.80 | CTSS (0.80) | CTSSCTSLCTSK | |
| SCHEMBL3836140 | 0.78 | CTSS (0.51) | CTSSCTSLCTSK | |
| SCHEMBL3835476 | 0.78 | CTSS (0.48) | CTSSCTSLCTSK | |
| SCHEMBL3020740 | 0.77 | CTSS (0.55) | CTSSCTSLCTSK | |
| SCHEMBL3840952 | 0.76 | CTSS (0.82) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658267-B1 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2009-10-14 | — | — | EP | claimed |