Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 16/20 | 0.50 |
| ▸ | CTSL | P07711 | 14/20 | 0.50 |
| ▸ | CTSK | P43235 | 11/20 | 0.50 |
| ▸ | KLK7 | P49862 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8290917 | 0.87 | CTSS (0.62) | CTSSCTSLCTSK | |
| SCHEMBL3837674 | 0.81 | CTSS (0.64) | CTSSCTSLCTSK | |
| SCHEMBL3010805 | 0.80 | CTSS (0.64) | CTSSCTSLCTSK | |
| SCHEMBL3010810 | 0.80 | CTSS (0.64) | CTSSCTSLCTSK | |
| SCHEMBL3839482 | 0.80 | CTSS (0.64) | CTSSCTSLCTSK | |
| SCHEMBL3010808 | 0.80 | CTSS (0.64) | CTSSCTSLCTSK | |
| SCHEMBL3836140 | 0.79 | CTSS (0.51) | CTSSCTSLCTSK | |
| SCHEMBL3835476 | 0.79 | CTSS (0.48) | CTSSCTSLCTSK | |
| SCHEMBL3023325 | 0.78 | ALDH1A1 (0.49) | CTSSCTSLCTSKKLK7 | |
| SCHEMBL3837319 | 0.73 | CTSS (0.47) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658267-B1 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2009-10-14 | — | — | EP | claimed |