SCHEMBL3839488

SCHEMBL3839488

Cc1ccc(C[SiH2]N[SiH3])cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.41
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
AGXT P21549 2/20 0.37
HTT P42858 1/20 0.36
CHRM2 P08172 1/20 0.36
ACHE P22303 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
POLB P06746 2/20 0.35
LMNA P02545 2/20 0.35
MAPT P10636 2/20 0.34
HPGD P15428 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HSP90AA1 P07900 1/20 0.34
HSP90AB1 P08238 1/20 0.34
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9994731 0.69 CHRM2 (0.50) IDO1CYP1A2CYP2A6TAAR1SMN1; SMN2
SCHEMBL28826465 0.69 IDO1 (0.46) IDO1CYP1A2CYP2A6TAAR1AGXT
SCHEMBL28179087 0.69 IDO1 (0.46) IDO1CYP1A2CYP2A6TAAR1SMN1; SMN2
P-Xylene SCHEMBL5146887 0.68 ACHE (0.67) IDO1CYP2A6ACHETDP1LMNA
SCHEMBL6114221 0.65 ALDH1A1 (0.50) IDO1CYP1A2CYP2A6TAAR1SMN1; SMN2
SCHEMBL15102980 0.65 AGXT (0.43) IDO1CYP1A2CYP2A6TAAR1AGXT
SCHEMBL6426239 0.64
SCHEMBL1149394 0.63 IDO1 (0.58) IDO1CYP1A2CYP2A6TAAR1AGXT
SCHEMBL11288839 0.63 CYP1A2 (0.68) IDO1CYP1A2CYP2A6TAAR1AGXT
SCHEMBL143961 0.63 CYP1A2 (0.68) IDO1CYP1A2CYP2A6TAAR1AGXT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090010673-A1 FILTER AND METHOD OF MANUFACTURING THE SAME NEC CORPORATION (JP) 2009-01-08 US disclosed