Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2206469 | 0.84 | PSIP1 (0.46) | PSIP1 | |
| SCHEMBL97872 | 0.80 | KEAP1 (0.48) | KEAP1 | |
| SCHEMBL2540301 | 0.79 | ALDH1A1 (0.40) | PSIP1 | |
| SCHEMBL5478677 | 0.79 | CA12 (0.31) | PSIP1 | |
| SCHEMBL5487764 | 0.79 | PSIP1 (0.33) | PSIP1 | |
| SCHEMBL8668452 | 0.78 | MAPT (0.39) | PSIP1 | |
| SCHEMBL8744622 | 0.78 | KDM4E (0.45) | — | |
| SCHEMBL8669528 | 0.77 | AR (0.45) | — | |
| SCHEMBL3767524 | 0.76 | KMT2A (0.50) | — | |
| SCHEMBL5119165 | 0.76 | PTGES2 (0.33) | PSIP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108020-A2 | 1-H-PYRAZOLO[3,4B]PYRIMIDINE DERIVATIVES AND THEIR USE AS MODULATORS OF MITOTIC KINASES | Biogen Idec MA, Inc. (US) | 2009-10-14 | — | — | EP | claimed |
| WO-2008094602-A2 | 1-H-PYRAZOLO (3,4B) PYRIMIDINE DERIVATIVES AND THEIR USE AS MODULATORS OF MITOTIC KINASES | BIOGEN IDEC MA INC. (US) | 2008-08-07 | — | — | WO | claimed |
| EP-2108020-A2 | 1-H-PYRAZOLO[3,4B]PYRIMIDINE DERIVATIVES AND THEIR USE AS MODULATORS OF MITOTIC KINASES | Biogen Idec MA, Inc. (US) | 2009-10-14 | — | — | EP | disclosed |
| WO-2008094602-A2 | 1-H-PYRAZOLO (3,4B) PYRIMIDINE DERIVATIVES AND THEIR USE AS MODULATORS OF MITOTIC KINASES | BIOGEN IDEC MA INC. (US) | 2008-08-07 | — | — | WO | disclosed |