Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9803869 | 0.80 | FFAR1 (0.42) | HPGDLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL9326656 | 0.80 | HRH3 (0.48) | GLAHPGDMEN1KMT2A | |
| SCHEMBL5674985 | 0.80 | LOXL2 (0.46) | HPGDSMN1; SMN2MAPK1MEN1ALDH1A1 | |
| SCHEMBL10467351 | 0.80 | FFAR1 (0.42) | HPGDLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL7898905 | 0.79 | HTR1B (0.42) | LMNAALDH1A1KMT2A | |
| SCHEMBL9432799 | 0.79 | POLB (0.49) | MMP3MMP9LMNAKMT2A | |
| SCHEMBL1745276 | 0.79 | CAPN1 (0.45) | HPGD | |
| SCHEMBL7911563 | 0.79 | HRH3 (0.42) | HPGDLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL4940660 | 0.78 | GAA (0.44) | ALDH1A1CYP2C19 | |
| SCHEMBL15065439 | 0.77 | ALDH1A1 (0.49) | LMNAMAPK1MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2009013091-A | PRODUCTION METHOD OF PIOGLITAZONE HYDROCHLORIDE | TOKUYAMA CORP | 2009-01-22 | — | — | JP | disclosed |