Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 2/20 | 0.93 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.50 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanine SCHEMBL20797883 | 1.00 | PNP (0.93) | PNPALDH1A1KDM4EMEN1MAPT | |
| Guanine SCHEMBL28088512 | 0.98 | PNP (0.90) | PNPALDH1A1KDM4EMEN1MAPT | |
| Guanine SCHEMBL986801 | 0.96 | PNP (1.00) | PNPALDH1A1KDM4EMEN1MAPT | |
| Guanine SCHEMBL5260 | 0.96 | PNP (1.00) | PNPALDH1A1KDM4EMEN1MAPT | |
| Guanine SCHEMBL1264884 | 0.96 | PNP (1.00) | PNPALDH1A1KDM4EMEN1MAPT | |
| Guanine SCHEMBL9511597 | 0.95 | PNP (0.96) | PNPALDH1A1KDM4EMEN1MAPT | |
| Guanine SCHEMBL22533907 | 0.95 | PNP (0.96) | PNPALDH1A1KDM4EMEN1MAPT | |
| Guanine SCHEMBL21611718 | 0.95 | PNP (0.96) | PNPALDH1A1KDM4EMEN1MAPT | |
| Guanine SCHEMBL2895089 | 0.95 | PNP (0.96) | PNPALDH1A1KDM4EMEN1MAPT | |
| Guanine SCHEMBL30967430 | 0.95 | PNP (0.96) | PNPALDH1A1KDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 20055 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024138129-A2 | ADENO-ASSOCIATED VIRUS FORMULATIONS | SPARK THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | WO | claimed |
| CN-118222531-A | Hypoxanthine-guanine phosphoribosyl transferase mutant and application thereof | 浙江大学 | 2024-06-21 | — | — | CN | claimed |
| CN-112213491-B | Kit for rapidly detecting drugs in hair and application of kit | 自然资源部第三海洋研究所 | 2024-04-12 | — | — | CN | claimed |
| WO-2024074705-A1 | CO-TREATMENT FOR GENE THERAPY | Hansa Biopharma AB (SE) | 2024-04-11 | — | — | WO | claimed |
| EP-4349365-A1 | CO-TREATMENT FOR GENE THERAPY | Hansa Biopharma AB (SE) | 2024-04-10 | — | — | EP | claimed |
| CN-117836327-A | Engineered chimeric fusion protein compositions and methods of use thereof | 美洛德生物医药公司 | 2024-04-05 | — | — | CN | claimed |
| CN-117757867-A | Method for synthesizing 5-phosphoribosyl by hypoxanthine-guanine phosphoribosyl transferase and application thereof | 浙江大学 | 2024-03-26 | — | — | CN | claimed |
| CN-117720641-A | Preparation method of drug-loaded human serum albumin combined monoclonal antibody | 台州市耶大基因与细胞治疗研究院 | 2024-03-19 | — | — | CN | claimed |
| CN-114315705-B | URAT1 inhibitor, preparation method and application thereof | 杭州中美华东制药有限公司 | 2024-02-20 | — | — | CN | claimed |
| CN-114315715-B | URAT1 inhibitor, and preparation method and application thereof | 杭州中美华东制药有限公司 | 2024-02-20 | — | — | CN | claimed |
| EP-0285511-B1 | IMMUNOASSAY OF THROMBOMODULIN | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1992-11-25 | — | — | EP | claimed |
| US-5126253-A | Production of monoclonal antibodies | SUNTORY LIMITED (JP) | 1992-06-30 | — | — | US | claimed |
| EP-0487611-A1 | HERPES SIMPLEX VIRUS TYPE 1 MUTANT. | BRITISH TECH GROUP (GB) | 1992-06-03 | — | — | EP | claimed |
| EP-0114670-B1 | NOVEL CELL LINES FOR USE IN THE PREPARATION OF HYBRIDOMA CELLS | SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) | 1991-10-02 | — | — | EP | claimed |
| WO-1991002788-A1 | HERPES SIMPLEX VIRUS TYPE 1 MUTANT | BRITISH TECHNOLOGY GROUP PLC (GB) | 1991-03-07 | — | — | WO | claimed |
| EP-0286099-A2 | Monoclonal antibodies reactive with endotoxin core | VELOS GROUP (US) | 1988-10-12 | — | — | EP | claimed |
| EP-0260829-A2 | Antibodies reactive with chlorinated phenols and methods of preparing and using same | WESTINGHOUSE ELECTRIC CORPORATION (US) | 1988-03-23 | — | — | EP | claimed |
| EP-0258006-A2 | Monoclonal antibodies reactive with chlorinated dibenzo-p-dioxins and method of preparing and using same | WESTINGHOUSE ELECTRIC CORPORATION (US) | 1988-03-02 | — | — | EP | claimed |
| EP-0183571-A2 | Cosmid vectors | BANYU SEIYAKU KABUSHIKI KAISHA (JP) | 1986-06-04 | — | — | EP | claimed |
| EP-0114670-A2 | Novel cell lines for use in the preparation of hybridoma cells | SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) | 1984-08-01 | — | — | EP | claimed |