Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3841106 | 0.98 | THRA (0.38) | THRATHRBPLA2G4B | |
| SCHEMBL3291240 | 0.92 | PPARA (0.35) | THRATHRB | |
| SCHEMBL3846160 | 0.91 | THRA (0.35) | THRATHRBPLA2G4B | |
| SCHEMBL3284699 | 0.90 | THRA (0.36) | THRATHRBPLA2G4B | |
| SCHEMBL3843626 | 0.89 | THRA (0.36) | THRATHRBPLA2G4B | |
| SCHEMBL3285973 | 0.81 | MAPK14 (0.36) | THRATHRB | |
| SCHEMBL3844604 | 0.80 | KMT2A (0.36) | PLA2G4B | |
| SCHEMBL3846400 | 0.80 | MAPK14 (0.37) | THRATHRBPLA2G4B | |
| SCHEMBL3844116 | 0.80 | PLA2G4B (0.38) | PLA2G4B | |
| SCHEMBL3844113 | 0.76 | ALOX5 (0.36) | PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | disclosed |