Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3846160 | 0.98 | THRA (0.35) | THRATHRBPLA2G4BCYSLTR2CYSLTR1 | |
| SCHEMBL3841106 | 0.91 | THRA (0.38) | THRATHRBPLA2G4BCYSLTR2CYSLTR1 | |
| SCHEMBL3841339 | 0.89 | THRA (0.36) | THRATHRBPLA2G4B | |
| SCHEMBL3846400 | 0.88 | MAPK14 (0.37) | THRATHRBPLA2G4B | |
| SCHEMBL3284699 | 0.86 | THRA (0.36) | THRATHRBPLA2G4BCYSLTR2CYSLTR1 | |
| SCHEMBL3291240 | 0.85 | PPARA (0.35) | THRATHRBSMPD1 | |
| SCHEMBL3846159 | 0.83 | GGPS1 (0.36) | PLA2G4BCYSLTR2CYSLTR1SMPD1GGPS1 | |
| SCHEMBL3844912 | 0.81 | PPARG (0.35) | PLA2G4BCYSLTR2CYSLTR1SMPD1GGPS1 | |
| SCHEMBL3285973 | 0.74 | MAPK14 (0.36) | THRATHRB | |
| SCHEMBL3844116 | 0.73 | PLA2G4B (0.38) | PLA2G4BCYSLTR2CYSLTR1SMPD1GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |