SCHEMBL3841441

SCHEMBL3841441

C#CC(Oc1cc[c]cc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3841553 0.79
SCHEMBL6503944 0.75 KIF11 (0.36) TSHRALDH1A1
SCHEMBL11419604 0.72 MAPK1 (0.50) TSHRALDH1A1
SCHEMBL3095108 0.72 TSHR (0.39) TSHRALDH1A1
SCHEMBL3645414 0.72 TSHR (0.39) TSHRALDH1A1
SCHEMBL3843067 0.69 ELANE (0.35)
SCHEMBL28724152 0.69 TSHR (0.39) TSHRALDH1A1GAA
SCHEMBL2105595 0.68 TSHR (0.34) TSHRALDH1A1
SCHEMBL3849553 0.68 ALDH1A1 (0.31) TSHRALDH1A1
SCHEMBL14141808 0.67 KIF11 (0.35) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090318610-A1 ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES SUMITOMO BAKELITE CO., LTD (JP) 2009-12-24 US disclosed
EP-2117009-A1 ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Co., Ltd. (JP) 2009-11-11 EP disclosed