SCHEMBL3841490

SCHEMBL3841490

CC#Cc1cc(C#CC)cc(C23CC4CC(C2)CC(C2C5CC6CC(C5)CC2(c2cc(C#CC)cc(C#CC)c2)C6)(C4)C3)c1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.34
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3841874 0.86 GRIN2D (0.36) PGRALDH1A1
SCHEMBL3843224 0.85 PGR (0.33) PGRALDH1A1
SCHEMBL3840670 0.76 ALDH1A1 (0.32) ALDH1A1LMNA
SCHEMBL2188872 0.76 PGR (0.42) PGRALDH1A1LMNA
SCHEMBL3848550 0.76 GRIN2D (0.30)
SCHEMBL3848547 0.76 GRIN2D (0.30)
SCHEMBL3841585 0.76 GRIN2D (0.31)
SCHEMBL3841910 0.74 ESR1 (0.43) PGRALDH1A1LMNA
SCHEMBL2189181 0.73 PGR (0.43) PGRALDH1A1LMNA
SCHEMBL3842496 0.72 GRIN2D (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090318610-A1 ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES SUMITOMO BAKELITE CO., LTD (JP) 2009-12-24 US disclosed
EP-2117009-A1 ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Co., Ltd. (JP) 2009-11-11 EP disclosed