Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3865049 | 0.90 | SLC6A1 (0.55) | SLC6A1ALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL3841038 | 0.88 | SLC6A1 (0.54) | SLC6A1ALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL3839566 | 0.88 | SLC6A1 (0.54) | SLC6A1ALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL3842807 | 0.83 | SLC6A1 (0.50) | SLC6A1ALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL3842797 | 0.83 | ALDH1A1 (0.55) | SLC6A1ALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL28959996 | 0.82 | BCHE (0.55) | CYP1A2CYP2D6CYP2C9TSHRNFKB1 | |
| SCHEMBL3839600 | 0.81 | CYP1A2 (0.55) | CYP1A2SMN1; SMN2 | |
| SCHEMBL3840286 | 0.81 | SLC6A1 (0.54) | SLC6A1ALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL3840187 | 0.80 | BCHE (0.61) | SMN1; SMN2 | |
| SCHEMBL3838182 | 0.79 | SLC6A1 (0.52) | SLC6A1ALDH1A1LMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931341-B1 | 1H-INDOLE-PYRIDINECARBOXAMIDE AND 1H-INDOLE-PIPERIDINECARBOXAMIDE DERIVATIVES AND THEIR USE AS TYROSINE HYDROXYLASE INDUCERS | SERVIER LAB (FR) | 2009-11-04 | — | — | EP | disclosed |