⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015054 | 0.78 | — | — | |
| SCHEMBL1246327 | 0.71 | TSHR (0.30) | — | |
| SCHEMBL706065 | 0.71 | CHRM1 (0.35) | — | |
| SCHEMBL2357015 | 0.70 | TDP1 (0.32) | — | |
| SCHEMBL288304 | 0.69 | — | — | |
| SCHEMBL25135495 | 0.69 | — | — | |
| SCHEMBL2648955 | 0.69 | DNM1 (0.47) | — | |
| SCHEMBL434841 | 0.67 | HDAC1 (0.39) | — | |
| SCHEMBL4448087 | 0.67 | — | — | |
| SCHEMBL7858145 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024083861-A1 | 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES DERIVATIVES AND USE THEREOF | SELABTEC SCIENCES, SLU (ES) | 2024-04-25 | — | — | WO | disclosed |
| EP-3813832-A1 | COMPOUNDS FOR USE IN PREVENTING OR TREATING CANCER | Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca (ES) | 2021-05-05 | — | — | EP | disclosed |
| EP-1885187-A4 | METHODS FOR TREATING DRUG RESISTANT CANCER | NOVARTIS AG (CH) | 2009-05-13 | — | — | EP | disclosed |
| EP-1539754-A4 | BENZIMIDAZOLE QUINOLINONES AND USES THEREOF | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2009-02-25 | — | — | EP | disclosed |
| EP-1885187-A2 | METHODS FOR TREATING DRUG RESISTANT CANCER | Novartis AG (CH) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006124413-A2 | METHODS FOR TREATING DRUG RESISTANT CANCER | NOVARTIS AG (CH) | 2006-11-23 | — | — | WO | disclosed |
| EP-1692085-A2 | INHIBITION OF FGFR3 AND TREATMENT OF MULTIPLE MYELOMA | Chiron Corporation (US) | 2006-08-23 | — | — | EP | disclosed |
| EP-1682529-A2 | METHODS FOR SYNTHESIZING QUINOLINONE COMPOUNDS | Chiron Corporation (US) | 2006-07-26 | — | — | EP | disclosed |
| EP-1539754-A2 | BENZIMIDAZOLE QUINOLINONES AND USES THEREOF | Chiron Corporation (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2005046590-A2 | METHODS FOR SYNTHESIZING QUINOLINONE COMPOUNDS | CHIRON CORPORATION (US) | 2005-05-26 | — | — | WO | disclosed |
| WO-2005047244-A2 | INHIBITION OF FGFR3 AND TREATMENT OF MULTIPLE MYELOMA | CHIRON CORPORATION (US) | 2005-05-26 | — | — | WO | disclosed |
| WO-2004018419-A2 | BENZIMIDAZOLE QUINOLINONES AND USES THEREOF | CHIRON CORPORATION (US) | 2004-03-04 | — | — | WO | disclosed |