SCHEMBL2357015

SCHEMBL2357015

CCCC(C)OCOCOC(C)CCC

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.32
TSHR P16473 1/20 0.32
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6176128 0.88 TSHR (0.35) TDP1TSHRLMNA
SCHEMBL23049066 0.82 TSHR (0.30) TSHR
SCHEMBL31365540 0.80 OPRM1 (0.41) TSHRLMNA
SCHEMBL15256790 0.77 GABRR1 (0.30)
SCHEMBL6374192 0.77
SCHEMBL3315438 0.77
SCHEMBL13011270 0.74
SCHEMBL2759866 0.74
SCHEMBL3411855 0.74
SCHEMBL16590938 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3268353-B1 PYRAZOLYL DERIVATIVES AS PEST CONTROL AGENTS BAYER ANIMAL HEALTH GMBH (DE) 2020-09-09 EP disclosed
US-10299478-B2 Pyrazolyltriazolylpyridines as pesticides BAYER ANIMAL HEALTH GMBH (DE) 2019-05-28 US disclosed
US-10273226-B2 Pyrazolyl-heteroarylamides as pesticides BAYER ANIMAL HEALTH GMBH (DE) 2019-04-30 US disclosed
EP-3157913-B1 PYRAZOLYL TRIAZOLYL PYRIDINES AS PESTICIDE BAYER ANIMAL HEALTH GMBH (DE) 2019-04-17 EP disclosed
US-10202351-B2 Pyrazolyl derivatives as pest control agents BAYER ANIMAL HEALTH GMBH (DE) 2019-02-12 US disclosed
EP-3089972-B1 NOVEL PYRAZOLE HETEROARYLAMIDES AS PESTICIDES BAYER ANIMAL HEALTH GMBH (DE) 2018-05-16 EP disclosed
US-20180044298-A1 NOVEL PYRAZOLYL DERIVATIVES AS PEST CONTROL AGENTS BAYER ANIMAL HEALTH GMBH (DE) 2018-02-15 US disclosed
EP-3268353-A1 PYRAZOLYL-DERIVATIVES AS PEST CONTROL AGENTS Bayer Animal Health GmbH (DE) 2018-01-17 EP disclosed
EP-2953942-B1 HALOGEN-SUBSTITUTED PYRAZOLE DERIVATIVES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2017-10-25 EP disclosed
EP-2964631-B1 HALOGEN-SUBSTITUTED N-[3-(1H-PYRAZOL-4-YL)PHENYLMETHYL]-SULFONAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PESTICIDES FOR USE IN CROP PROTECTION IN VETERINARY MEDICINE AND IN MATERIAL PROTECTION BAYER ANIMAL HEALTH GMBH (DE) 2017-08-30 EP disclosed
US-20100234312-A1 AVERMECTIN DERIVATIVES BAYER CROPSCIENCE AG (DE) 2010-09-16 US disclosed
EP-2054427-B1 AVERMECTIN DERIVATIVES BAYER CROPSCIENCE AG (DE) 2010-07-14 EP disclosed
WO-2010051926-A2 NEW HALOGEN-SUBSTITUTED BONDS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-05-14 WO disclosed
EP-2184273-A1 Halogen substituted compounds as pesticides Bayer CropScience AG (DE) 2010-05-12 EP disclosed
WO-2009141096-A1 SUBSTITUTED SPIRO-ISOXAZOLINES BAYER CROPSCIENCE AG (DE) 2009-11-26 WO disclosed
US-20090131406-A1 CROPWELLLINS AND SYNTHETIC DERIVATIVES THEREOF USED AS MEDICAMENTS BAYER CROPSCIENCE AG (DE) 2009-05-21 US disclosed
EP-2054427-A2 AVERMECTIN DERIVATIVES Bayer CropScience AG (DE) 2009-05-06 EP disclosed
EP-1896480-A1 CRIPOWELLINS AND SYNTHETIC DERIVATIVES THEREOF USED AS MEDICAMENTS Bayer CropScience Aktiengesellschaft (DE) 2008-03-12 EP disclosed
WO-2008019784-A2 AVERMECTIN DERIVATIVES BAYER CROPSCIENCE AG (DE) 2008-02-21 WO disclosed
WO-2006136309-A1 CRIPOWELLINS AND SYNTHETIC DERIVATIVES THEREOF USED AS MEDICAMENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2006-12-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180044298-A1 NOVEL PYRAZOLYL DERIVATIVES AS PEST CONTROL AGENTS PIR, PLPBP, PDXK TDP1 4016/4885TSHR 2264/4885LMNA 3421/4885
US-10299478-B2 Pyrazolyltriazolylpyridines as pesticides PRDX4, PRDX1, ATL3 TDP1 1253/4885TSHR 631/4885LMNA 3284/4885
US-20090131406-A1 CROPWELLLINS AND SYNTHETIC DERIVATIVES THEREOF USED AS MEDICAMENTS COIL, CIAPIN1, MEN1 TDP1 2823/4885TSHR 4683/4885LMNA 1932/4885
US-20100234312-A1 AVERMECTIN DERIVATIVES OXTR, C3AR1, CBR3 TDP1 2639/4885TSHR 20/4885LMNA 1728/4885
US-10273226-B2 Pyrazolyl-heteroarylamides as pesticides CYP4Z1, NAT1, CYP4F3 TDP1 2190/4885TSHR 766/4885LMNA 2335/4885
US-10202351-B2 Pyrazolyl derivatives as pest control agents PIR, PDXK, CTRL TDP1 1913/4885TSHR 1353/4885LMNA 3087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.