SCHEMBL3842528

SCHEMBL3842528

O=C(O)CC(Cc1ccccc1)C(=O)Nc1ccccc1

nearest known ligand 0.81

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CPA1 P15085 2/20 0.64
CPB1 P15086 1/20 0.64
CPA3 P15088 1/20 0.64
CPB2 Q96IY4 1/20 0.64
MEN1 O00255 1/20 0.62
KMT2A Q03164 1/20 0.62
LTA4H P09960 2/20 0.61
POLB P06746 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29154468 0.88 MEN1 (0.59) MEN1KMT2APOLB
SCHEMBL12335729 0.85 MEN1 (0.71) MEN1KMT2A
SCHEMBL7271417 0.83 MME (0.65) CPA3MEN1KMT2A
SCHEMBL2685653 0.79 CPA1 (0.72) CPA1CPB1CPA3CPB2LTA4H
SCHEMBL14853314 0.79 HDAC1 (0.61) MEN1KMT2APOLB
SCHEMBL11248580 0.79 CPA3 (0.72) CPA1CPB1CPA3CPB2LTA4H
SCHEMBL12517132 0.79 LTA4H (0.64) CPA1CPB1CPA3CPB2MEN1
SCHEMBL393002 0.78 CPA1 (1.00) CPA1CPB1CPA3CPB2LTA4H
SCHEMBL1915564 0.78 CPA1 (1.00) CPA1CPB1CPA3CPB2LTA4H
SCHEMBL5688996 0.78 CPA1 (1.00) CPA1CPB1CPA3CPB2LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1486488-B1 Use of a compound of formula I for making a pharmaceutical composition BIONDI RICARDO MIGUEL (DE) 2009-10-28 EP disclosed
US-20070032474-A1 Use of a compound of formula 1 for making a pharmaceutical composition BIONDI RICARDO M 2007-02-08 US disclosed
WO-2004111008-A2 USE OF A COMPOUND OF FORMULA I FOR MAKING A PHARMACEUTICAL COMPOSITION BIONDI RICARDO MIGUEL (DE) 2004-12-23 WO disclosed
EP-1486488-A1 Use of a compound of formula I for making a pharmaceutical composition Phosphosites GmbH (DE) 2004-12-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070032474-A1 Use of a compound of formula 1 for making a pharmaceutical composition CYP7A1, UGT1A1, CYP2F1 CPA1 156/4885CPB1 553/4885CPA3 304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.