SCHEMBL384263

SCHEMBL384263

CC(C)(C)c1cc(C(=O)O)ccc1O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 2/20 0.71
RARG P13631 2/20 0.71
RARA P10276 1/20 0.67
HSP90AA1 P07900 6/20 0.60
HSP90AB1 P08238 6/20 0.60
KDM4E B2RXH2 2/20 0.57
MAPT P10636 2/20 0.57
POLB P06746 2/20 0.57
CA12 O43570 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
GAA P10253 1/20 0.57
CA4 P22748 1/20 0.57
CA6 P23280 1/20 0.57
PTGS2 P35354 1/20 0.57
CA7 P43166 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
ALDH1A1 P00352 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29654169 1.00 RARB (0.71) RARBRARGRARAHSP90AA1HSP90AB1
SCHEMBL6847996 0.87 RARB (0.57) RARBRARGRARAHSP90AA1HSP90AB1
SCHEMBL8772445 0.87 ALDH1A1 (0.61) RARBRARGRARAHSP90AA1HSP90AB1
SCHEMBL4250217 0.87 RARB (0.57) RARBRARGRARAHSP90AA1HSP90AB1
Terephthalic Acid SCHEMBL27615418 0.85 RARB (0.60) RARBRARGRARAHSP90AA1HSP90AB1
Terephthalic Acid SCHEMBL7766110 0.85 RARB (0.60) RARBRARGRARAHSP90AA1HSP90AB1
E319 SCHEMBL10904762 0.85 TYR (0.69) RARBRARGRARAHSP90AA1HSP90AB1
SCHEMBL1730526 0.84 ESRRA (0.68) RARBRARGRARAHSP90AA1HSP90AB1
SCHEMBL2582866 0.84 POLB (0.59) RARBRARGRARAHSP90AA1HSP90AB1
SCHEMBL7054158 0.84 RARG (1.00) RARBRARGRARAHSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 362 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114920943-A Group-modified macromolecular polymer, and preparation method and application thereof 天津大学 2022-08-19 CN claimed
CN-113816940-A Nicotine salts, co-crystals and salt co-crystal complexes R.J.雷诺兹烟草公司 2021-12-21 CN claimed
CN-113754634-A Nicotine salts, co-crystals and salt co-crystal complexes R.J.雷诺兹烟草公司 2021-12-07 CN claimed
EP-0289802-B1 Optically anisotropic melt forming aromatic copolyesters based on t-butyl-4-hydroxybenzoic acid DU PONT (US) 1997-10-15 EP claimed
EP-0321107-B1 Thermotropic liquid-crystalline aromatic polyesters HIMONT ITALIA (IT) 1995-01-25 EP claimed
US-5235025-A Cross-linkable thermotropic liquid crystalline aromatic polyester HIMONT ITALIA S.R.L. (IT) 1993-08-10 US claimed
US-5015721-A Thermotropic liquid-crystalline aromatic, polyesters MONTEDISON S.P.A. (IT) 1991-05-14 US claimed
US-4978735-A Thermotropic liquid crystalline aromatic polyester from 3,3'-diphenyl-4,4'-d HIMONT ITALIA S.R.L. (IT) 1990-12-18 US claimed
EP-0383177-A2 Cross-linkable thermotropic liquid crystalline aromatic polyesters HIMONT ITALIA S.r.l. (IT) 1990-08-22 EP claimed
US-4923955-A Thermotropic liquid-crystalline aromatic polyesters of substituted 4,4'-dihydroxy-diphenylene MONTEDISON S.P.A. (IT) 1990-05-08 US claimed
EP-0324608-A2 Thermotropic liquid crystalline aromatic polyesters Montedison S.p.A. (IT) 1989-07-19 EP claimed
EP-0323710-A1 Thermotropic liquid crystalline aromatic polyesters Montedison S.p.A. (IT) 1989-07-12 EP claimed
EP-0321107-A1 Thermotropic liquid-crystalline aromatic polyesters HIMONT ITALIA S.r.l. (IT) 1989-06-21 EP claimed
EP-0289802-A2 Optically anisotropic melt forming aromatic copolyesters based on t-butyl-4-hydroxybenzoic acid E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-11-09 EP claimed
US-4746566-A Optically anisotropic melt forming aromatic copolyesters based on t-butyl-4-hydroxybenzoic acid E. I. DUPONT DE NEMOURS AND COMPANY (US) 1988-05-24 US claimed
US-4447593-A HIGH STRENGTH; MELT-SHAPEABLE; TEIJIN LIMITED (JP) 1984-05-08 US claimed
US-20260107968-A1 END PLUG COMPRISING A SUBSTITUTED 3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE RAI STRATEGIC HOLDINGS INC (US) 2026-04-23 US disclosed
US-20260107973-A1 AEROSOL-MODIFYING ADDITIVE COMPRISING A SUBSTITUTED 3-(1 METHYLPYRROLIDIN-2-YL)PYRIDINE RAI STRATEGIC HOLDINGS INC (US) 2026-04-23 US disclosed
US-4125675-A Color developing sheet with organic developer and latex binder SUMITOMO NAUGATUCK CO., LTD. (JP) 1978-11-14 US disclosed
US-4046941-A PRESSURE SENSITIVE COPYING SANKO CHEMICAL COMPANY LTD. (JA) 1977-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260107968-A1 END PLUG COMPRISING A SUBSTITUTED 3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE ALK, EXOSC4, EXOSC9 RARB 3839/4885RARG 2917/4885RARA 3073/4885
US-20260107973-A1 AEROSOL-MODIFYING ADDITIVE COMPRISING A SUBSTITUTED 3-(1 METHYLPYRROLIDIN-2-YL)PYRIDINE CHRM3, CHRM1, CHRM2 RARB 2504/4885RARG 1633/4885RARA 1703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.