Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | TYR | P14679 | 2/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | MIF | P14174 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | RARB | P10826 | 2/20 | 0.58 |
| ▸ | RARG | P13631 | 2/20 | 0.58 |
| ▸ | RARA | P10276 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 6/20 | 0.49 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA7 | P43166 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| E319 SCHEMBL10904762 | 0.87 | TYR (0.69) | ALDH1A1HTTTYRNR1I2LMNA | |
| SCHEMBL29654169 | 0.87 | RARB (0.71) | ALDH1A1HTTTYRNR1I2LMNA | |
| SCHEMBL384263 | 0.87 | RARB (0.71) | ALDH1A1HTTTYRNR1I2LMNA | |
| SCHEMBL29654078 | 0.85 | ALDH1A1 (0.57) | ALDH1A1HTTTYRNR1I2LMNA | |
| SCHEMBL1355541 | 0.85 | TDP1 (0.54) | RARBRARGRARACA12CA1 | |
| SCHEMBL38809 | 0.85 | ALDH1A1 (0.57) | ALDH1A1HTTTYRNR1I2LMNA | |
| E319 SCHEMBL31517209 | 0.83 | ALDH1A1 (0.67) | ALDH1A1HTTTYRNR1I2LMNA | |
| E319 SCHEMBL6674211 | 0.83 | ALDH1A1 (0.67) | ALDH1A1HTTTYRNR1I2LMNA | |
| SCHEMBL28521424 | 0.82 | TDP1 (0.51) | RARBRARGRARACA12CA1 | |
| E319 SCHEMBL5016006 | 0.81 | ALDH1A1 (0.65) | ALDH1A1HTTTYRNR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289802-B1 | Optically anisotropic melt forming aromatic copolyesters based on t-butyl-4-hydroxybenzoic acid | DU PONT (US) | 1997-10-15 | — | — | EP | claimed |