Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.60 |
| ▸ | RARG | P13631 | 2/20 | 0.60 |
| ▸ | RARA | P10276 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | ESRRA | P11474 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL27615418 | 1.00 | RARB (0.60) | RARBRARGRARAALDH1A1SMN1; SMN2 | |
| SCHEMBL29654169 | 0.85 | RARB (0.71) | RARBRARGRARAALDH1A1SMN1; SMN2 | |
| SCHEMBL384263 | 0.85 | RARB (0.71) | RARBRARGRARAALDH1A1SMN1; SMN2 | |
| Acetone SCHEMBL28158510 | 0.85 | ALDH1A1 (0.55) | RARBRARGRARAALDH1A1SMN1; SMN2 | |
| SCHEMBL270433 | 0.85 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2HSP90AA1HSP90AB1CSNK2A1 | |
| SCHEMBL29359626 | 0.85 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2HSP90AA1HSP90AB1CSNK2A1 | |
| SCHEMBL6847996 | 0.84 | RARB (0.57) | RARBRARGRARAALDH1A1SMN1; SMN2 | |
| SCHEMBL11865746 | 0.83 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HSP90AA1HSP90AB1CSNK2A1 | |
| SCHEMBL11673542 | 0.83 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HSP90AA1HSP90AB1CSNK2A1 | |
| SCHEMBL28427877 | 0.83 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HSP90AA1HSP90AB1CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539675-A | Stable resin composition | SABIC环球技术有限责任公司 | 2022-05-27 | — | — | CN | claimed |
| CN-1034931-A | Stablizer by coating makes polyolefine in in-reactor stabilization | SHELL OIL CO (US) | 1989-08-23 | — | — | CN | claimed |
| CN-1033060-A | The preparation method of stable olefin compound | SHELL OIL CO (US) | 1989-05-24 | — | — | CN | claimed |
| EP-4700085-A1 | THERMOPLASTIC RESIN COMPOSITION, METHOD FOR PRODUCING SAME, AND MOLDED ARTICLE INCLUDING SAME | LG CHEM, LTD. (KR) | 2026-02-25 | — | — | EP | disclosed |
| EP-4700081-A1 | THERMOPLASTIC RESIN COMPOSITION, METHOD FOR PREPARING SAME, AND MOLDED ARTICLE COMPRISING SAME | LG Chem, Ltd. (KR) | 2026-02-25 | — | — | EP | disclosed |
| EP-4700086-A1 | THERMOPLASTIC RESIN COMPOSITION, PREPARATION METHOD THEREFOR, AND MOLDED ARTICLE INCLUDING SAME | LG CHEM, LTD. (KR) | 2026-02-25 | — | — | EP | disclosed |
| US-12540241-B2 | Thermoplastic resin composition, method of preparing the same, and molded article including the same | LG CHEM, LTD. (KR) | 2026-02-03 | — | — | US | disclosed |
| EP-4685188-A1 | THERMOPLASTIC RESIN COMPOSITION, PREPARATION METHOD THEREFOR AND MOLDED ARTICLE COMPRISING SAME | LG Chem, Ltd. (KR) | 2026-01-28 | — | — | EP | disclosed |
| EP-4098698-B1 | THERMOPLASTIC RESIN COMPOSITION, METHOD OF PREPARING SAME, AND MOLDED ARTICLE COMPRISING SAME | LG CHEMICAL LTD (KR) | 2026-01-28 | — | — | EP | disclosed |
| EP-4592347-A1 | THERMOPLASTIC RESIN COMPOSITION, METHOD FOR PRODUCING SAME, AND MOLDED ARTICLE INCLUDING SAME | LG Chem, Ltd. (KR) | 2025-07-30 | — | — | EP | disclosed |
| US-20250236727-A1 | THERMOPLASTIC RESIN COMPOSITION, METHOD OF PREPARING THE SAME, AND MOLDED ARTICLE INCLUDING THE SAME | LG CHEM, LTD. (KR) | 2025-07-24 | — | — | US | disclosed |
| CN-1028027-C | Ethylene/pentene-1 copolymer, process for preparation of same, and ethylene/pentene-1 copolymer composition | MITSUI PETROCHEMICAL IND (JP) | 1995-03-29 | — | — | CN | disclosed |
| CN-1064689-A | Ethylene/pentene-1 copolymer composition | MITSUI PETROCHEMICAL IND (JP) | 1992-09-23 | — | — | CN | disclosed |
| CN-1064690-A | Ethylene/pentene-1 copolymer composition | MITSUI PETROCHEMICAL IND (JP) | 1992-09-23 | — | — | CN | disclosed |
| CN-1064489-A | Ethylene/pentene-1 copolymer film and ethylene/pentene-1 copolymer composition film | MITSUI PETROCHEMICAL IND (JP) | 1992-09-16 | — | — | CN | disclosed |
| CN-1055368-A | Ethylene/pentene-1 copolymer and preparation method thereof, and ethylene/pentene-1 copolymer composition | MITSUI PETROCHEMICAL IND (JP) | 1991-10-16 | — | — | CN | disclosed |
| CN-1054425-A | Ethylene/1-pentene copolymer, process for preparing the same and ethylene/1-pentene copolymer composition | MITSUI PETROCHEMICAL IND (JP) | 1991-09-11 | — | — | CN | disclosed |
| CN-1039432-A | Polyolefins compound of superhigh molecular weight | MITSUI PETROCHEMICAL IND (JP) | 1990-02-07 | — | — | CN | disclosed |
| CN-1034931-A | Stablizer by coating makes polyolefine in in-reactor stabilization | SHELL OIL CO (US) | 1989-08-23 | — | — | CN | disclosed |
| CN-1033060-A | The preparation method of stable olefin compound | SHELL OIL CO (US) | 1989-05-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12540241-B2 | Thermoplastic resin composition, method of preparing the same, and molded article including the same | MYB, CRBN, CYC1 | RARB 3485/4885RARG 2792/4885RARA 2784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.